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Tachipirina Painkiller 500 mg 20 Tablets

Tachipirina Painkiller 500 mg 20 Tablets

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Tachipirina 500 mg is a paracetamol-based over-the-counter drug with pain reliever, antipyretic and anti-inflammatory action . Tachipirina 20 Tablets is an antipyretic indicated in the symptomatic treatment of febrile diseases such as flu, exanthematous diseases, acute respiratory tract diseases or.

Paracetamol is an antipyretic suitable for treating fever in children , lowering the temperature and controlling flu symptoms.

Paracetamol is a painkiller and analgesic useful in case of headaches, neuralgia, myalgia and other painful manifestations of medium size and of various origins.

Dosage and method of use of Tachipirina Painkiller 500 mg 20 Tablets

How to take Tachipirina 500 mg?

For children it is essential to respect the dosage defined according to their body weight , and therefore to choose the most suitable formulation.

500 mg tablets

Children weighing between 21 and 25 kg (between 6.5 and less than 8 years): ½ tablet of Tachipirina 500 mg at a time, to be repeated if necessary after 4 hours, without exceeding 6 doses per day (3 tablets) .

Children weighing between 26 and 40 kg (between 8 and 11 years): 1 tablet at a time, to be repeated if necessary after 6 hours, without exceeding 4 doses per day.

Children weighing between 41 and 50 kg (between 12 and 15 years): 1 tablet at a time of Tachipirina 500 mg, to be repeated if necessary after 4 hours, without exceeding 6 doses per day.

Children weighing more than 50 kg (approximately over 15 years): 1 tablet at a time of Tachipirina 500 mg, to be repeated if necessary after 4 hours, without exceeding 6 doses per day.

Adults : 1 tablet at a time, to be repeated if necessary after 4 hours, without exceeding 6 doses per day. In case of severe pain or high fever, 2 tablets of 500 mg to be repeated if necessary after not less than 4 hours. The maximum oral dosage is 3000 mg

Active Ingredients and Excipients Tachipirina Painkiller 500 mg 20 Tablets

Each tablet of Tachipirina 500 mg 20 Tablets contains:

Active ingredient : Paracetamol 500 mg.

Excipients : microcrystalline cellulose, povidone, pregelatinised starch, stearic acid, croscarmellose sodium.

Contraindications Tachipirina Painkiller 500 mg 20 Tablets

Do not take Tachipirina Paracetamol 500 mg in case of:

  • Hypersensitivity to paracetamol or to any of the excipients
  • Patients suffering from severe haemolytic anemia (this contraindication does not refer to the 500mg oral formulations).
  • Severe hepatocellular insufficiency (this contraindication does not refer to the 500mg oral formulations).

Side effects Tachipirina Painkiller 500 mg 20 Tablets

Below are the undesirable effects of paracetamol organized according to the MedDRA system organ classification. There is insufficient data to establish the frequency of the individual effects listed.

  • Blood and lymphatic system disorders: Thrombocytopenia, leukopenia, anemia, agranulocytosis
  • Immune system disorders: Hypersensitivity reactions (urticaria, laryngeal edema, angioedema, anaphylactic shock)
  • Nervous system disorders: Vertigo
  • Gastrointestinal disorders Gastrointestinal reaction
  • Hepatobiliary disorders: Hepatic function abnormal, hepatitis
  • Skin and subcutaneous tissue disorders: Erythema multiforme, Stevens Johnson Syndrome, Epidermal necrolysis, rash
  • Renal and urinary disorders: Acute renal failure, interstitial nephritis, haematuria, anuria

Very rare cases of severe skin reactions have been reported. Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorization of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at.

Warnings Tachipirina Painkiller 500 mg 20 Tablets

In rare cases of allergic reactions, the administration should be discontinued and appropriate treatment instituted. Use with caution in case of chronic alcoholism, excessive alcohol intake (3 or more alcoholic drinks per day), anorexia, bulimia or cachexia, chronic malnutrition (low hepatic glutathione stores), dehydration, hypovolemia. Paracetamol should be administered with caution to patients with mild to moderate hepatocellular insufficiency (including Gilbert's syndrome), severe hepatic insufficiency (Child-Pugh>9), acute hepatitis, concomitant treatment with drugs affecting liver function, of glucose-6-phosphate dehydrogenase, haemolytic anemia. High or prolonged doses of the product can cause even serious alterations to the kidney and blood, therefore administration to subjects with renal insufficiency should only be carried out if actually necessary and under direct medical supervision. In case of prolonged use it is advisable to monitor the hepatic and renal function and the blood count. During treatment with paracetamol, before taking any other drug, check that it does not contain the same active ingredient, since serious adverse reactions may occur if paracetamol is taken in high doses. Invite the patient to contact the doctor before associating any other drug.

Interactions with other drugs Tachipirina 500 mg
Oral absorption of paracetamol depends on the rate of gastric emptying. Therefore, concomitant administration of drugs that slow down (e.g. anticholinergics, opioids) or increase (e.g. prokinetics) the rate of gastric emptying may result in a decrease or increase in the bioavailability of the product, respectively. Concomitant administration of cholestyramine reduces the absorption of paracetamol. The simultaneous intake of paracetamol and chloramphenicol can lead to an increase in the half-life of chloramphenicol, with the risk of increasing its toxicity. Concomitant use of paracetamol (4 g per day for at least 4 days) with oral anticoagulants may lead to slight variations in INR values. In these cases, more frequent monitoring of INR values ​​should be conducted during concomitant use and after its discontinuation. Use with extreme caution and under strict supervision during chronic treatment with drugs that can cause hepatic monooxygenase induction or in case of exposure to substances that can have this effect (e.g. rifampicin, cimetidine, antiepileptics such as glutethimide, phenobarbital, carbamazepine) . The same is true in cases of alcoholism and in patients treated with zidovudine. The administration of paracetamol can interfere with the determination of uric acid (by means of the phosphotungstic acid method) and with that of glycemia (by means of the glucose-oxidase-peroxidase method).

Tachypirine overdose 500 mg
There is a risk of intoxication, especially in patients with liver disease, in cases of chronic alcoholism, in patients with chronic malnutrition, and in patients receiving enzyme inducers. In these cases the overdose can be fatal. Symptoms In case of accidental assumption of very high doses of paracetamol, acute intoxication manifests itself with anorexia, nausea and vomiting followed by profound deterioration of the general conditions; these symptoms usually appear within the first 24 hours. In case of overdose, paracetamol can cause hepatic cytolysis which can evolve towards massive and irreversible necrosis, with consequent hepatocellular insufficiency, metabolic acidosis and encephalopathy, which can lead to coma and death. Simultaneously, an increase in the levels of hepatic transaminases, lactate dehydrogenase, and bilirubinemia, and a reduction in the levels of prothrombin are observed, which can occur in the 12-48 hours following ingestion. Treatment The measures to be taken consist of early gastric emptying and hospitalization for the necessary treatment, by administering, as early as possible, N-acetylcysteine ​​as an antidote: the dosage is 150 mg/kg iv in glucose solution in 15 minutes , then 50 mg/kg over the next 4 hours and 100 mg/kg over the next 16 hours, for a total of 300 mg/kg over 20 hours.

Pregnancy and lactation Tachipirina Painkiller 500 mg 20 Tablets

Can I take Tachipirina 500 mg when pregnant or breastfeeding?

Although clinical studies in pregnant or breastfeeding patients have not shown any particular contraindications to the use of paracetamol or caused undesirable effects on the mother or child, it is advisable to administer the product only in cases of real need and under direct medical supervision .

Expiration and storage of Tachipirina Painkiller 500 mg 20 Tablets

How to store Tachipirina 500 mg?

No special precautions for storage.



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