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Pursennid 30 Laxative Tablets 12 mg

Pursennid 30 Laxative Tablets 12 mg

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Pursennid Laxative Tablets is a preparation based on active ingredients extracted from the senna plant with a laxative action . Pursennid Laxative Tablets is indicated in cases of occasional constipation, difficulty in passing stools and hard stools.

Pursennid Laxative Tablets act in 6-12 hours, via stimulation of the large intestine, activating the evacuation of feces approximately 8 hours after intake .

Dosage and method of use of Pursennid 30 Laxative Tablets 12 mg

How to take Pursennid 30 Laxative Tablets 12 mg?

Dosage Adults and children over 12 years of age : 2–4 coated tablets of Pursennid per day.

Children between 10 and 12 years : 1–2 coated tablets per day of Pursennid Laxative Tablets.

Pediatric population: Contraindicated in children under 10 years of age.

Take preferably in the evening. The action of Pursennid occurs after 6–12 hours. Administered in the evening, the effect of Pursennid appears the next morning.
Swallow together with an adequate quantity of water (a large glass). A diet rich in liquids favors the effect of Pursennid Laxative Tablets 12 mg.

Active ingredients and excipients Pursennid 30 Laxative Tablets 12 mg

One Pursennid coated tablet contains:

Active ingredient : Sennosides A + B (as calcium salts) 12 mg.

Excipients : Lactose monohydrate; stearic acid; talc; cornstarch; anhydrous glucose; sucrose; Arabic gum; anhydrous colloidal silica; titanium dioxide, cetyl palmitate.

Contraindications Pursennid 30 Laxative Tablets 12 mg

Hypersensitivity to the active substance or to any of the excipients listed in paragraph 6.1. Contraindicated if the following medical conditions exist: – Inflammatory diseases of the digestive system (i.e. Crohn's disease, ulcerative colitis, liver disease, peritonitis and inflammatory intestinal diseases). – Irritation or obstruction of the gastrointestinal tract (i.e. spastic constipation, ileum/preileum obstruction, cramps and pain, nausea, vomiting and colic). – Abdominal symptoms that may be due to an undiagnosed underlying condition, such as acute intestinal conditions that may require surgery (i.e. acute diverticulitis, appendicitis and massive diarrhea). – states of severe dehydration, with loss of water and electrolytes, especially hypokalemia. Contraindicated in children under 10 years of age.

Side effects Pursennid 30 Laxative Tablets 12 mg

This medicine may cause mild abdominal discomfort such as abdominal pain, cramps, irritation of the colonic and gastric mucosa. Other effects such as dehydration, hypotension, fatigue, myopathies, stomach pain, hyponatremia, renal disorders, secondary hyperaldosteronism, hypocalcemia and hypomagnesemia have also been reported. These adverse reactions are usually reversible once you stop taking the laxative. Prolonged use or overdose of this drug may cause nausea, diarrhea with excessive loss of electrolytes, especially potassium (hypokalemia). There is also the possibility of developing megacolon.

  • Gastrointestinal disorders: Megacolon, Abdominal pain, Diarrhoea, Nausea, Abdominal discomfort
  • Systemic disorders and conditions relating to the administration site: Not known Fatigue, Drug tolerance
  • Musculoskeletal and connective tissue disorders Not known Myopathy
  • Renal and urinary disorders: Not known Kidney problems. Not known Chromaturia.
  • Metabolism and nutrition disorders. Not known Hyperaldosteronism. Hypocalcemia, Hypomagnesemia, Dehydration, Hypokalemia, Hyponatraemia, Blood electrolytes decreased, Vascular disorders, Not known Hypotension

Warnings Pursennid 30 Laxative Tablets 12 mg

The established dose must not be exceeded. Prolonged indiscriminate use of laxatives can lead to addiction and a deterioration of intestinal functions. The lowest effective dosage should be used to restore normal intestinal function. If no improvement has been achieved in the intestine, the dosage can be increased under medical supervision. Products containing senna and sennosides should only be used if a therapeutic effect cannot be achieved through a change in diet or the administration of bulking agents. The use of these drugs requires medical supervision: – if no positive effects occur following treatment; – if use is prolonged beyond one week of treatment; – if symptoms persist or worsen; – after a laparotomy or abdominal surgery; – if skin rashes, nausea and vomiting are present; – in children between 10 and 12 years old; – during pregnancy and breastfeeding. Information relating to excipients – Lactose: patients suffering from rare hereditary problems of galactose intolerance, lactase deficiency, or glucose-galactose malabsorption should not take this medicine. – Glucose: patients suffering from rare problems of glucose-galactose malabsorption should not take this medicine. – Sucrose: patients suffering from rare hereditary problems of fructose intolerance, glucose-galactose malabsorption, or sucrase isomaltase insufficiency should not take this medicine.

Interactions Pursennid Laxative Tablets and other drugs
Concomitant use of other drugs that induce hypokalaemia (ie diuretics, adrenocorticosteroids and licorice) may increase electrolyte imbalance. Hypokalemia (resulting from abuse of laxatives taken for a long time) potentiates the action of cardiac glycosides and interferes with antiarrhythmic drugs, with other drugs that induce the return to sinus rhythm (quinidine) and with drugs that induce lengthening of the Q–T interval.

Overdose Pursennid Laxative Tablets 12 mg
Symptoms The most important symptoms related to overdose/excessive use are abdominal colic and severe diarrhea resulting in losses of fluids and electrolytes, which must be replaced. Diarrhea especially can cause potassium loss, which can lead to cardiac disorders and muscle asthenia, particularly when cardiac glycosides, diuretics, adrenocorticosteroids or licorice root are administered at the same time. Management Treatment should be supportive with generous quantities of fluids. Electrolytes, especially potassium, should be monitored. This is especially important in the elderly. Chronic overdose of anthraquinone drugs can cause toxic hepatitis.

Pregnancy and breastfeeding Pursennid 30 Laxative Tablets 12 mgl

Can I take Pursennid 30 Laxative Tablets 12 mg while pregnant or breastfeeding?

Pregnancy There are no reports of side effects or harm during pregnancy and on the fetus at the recommended dosing regimen. However, following experimental data regarding the genotoxic risk of several anthraquinones, emodin and aloe-emodin, use during pregnancy is not recommended. Breastfeeding Use during breastfeeding is not recommended as there are insufficient data on the excretion of metabolites in breast milk. Small quantities of metabolites (rein) are excreted in breast milk. No laxative effect has been reported on breast-fed infants. Fertility Preclinical studies with sennosides do not indicate particular risks for fertility at therapeutically relevant doses.

Expiration and storage of Pursennid 30 Laxative Tablets 12 mg

How to store Pursennid Laxative Tablets 12 mg?

This medicine does not require any special storage conditions.



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