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Geffer Effervescent Granules 24 Sachets 5 g

Geffer Effervescent Granules 24 Sachets 5 g

Regular price €15,60 EUR
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Geffer Effervescent Granules is an over-the-counter drug based on Metoclopramide. Useful for treating the symptoms of hyperacidity (excess acid in the stomach), abnormal gas and wind in the stomach and digestive difficulties.

Geffer counteracts the symptoms of hyperacidity (pain and heartburn) even when accompanied by a slowdown in gastric transit (slow digestion). Reduces nausea, aerophagia and meteorism.

Dosage and method of use of Geffer Effervescent Granules 24 Sachets 5 g

How to take Geffer Effervescent Granules?

Take 1 sachet of Geffer Effervescent Granules in half a glass of water before meals or at the onset of symptoms, 2-3 times a day.

Do not exceed the recommended doses, especially elderly patients must adhere to the minimum dosages indicated above. The use of the product is restricted to adult patients .

Active Ingredients and Excipients Geffer Effervescent Granules 24 Sachets 5 g

Each sachet of Geffer Effervescent Granules contains:

Active ingredients: metoclopramide hydrochloride 5 mg, dimethicone 50 mg, potassium citrate 94.45 mg, citric acid 670 mg, tartaric acid 152 mg, sodium bicarbonate 1050 mg.

Excipients: Orange flavor, sucrose

Contraindications Geffer Effervescent Granules 24 Sachets 5 g

Do not take Geffer Effervescent Granules in case of:

  • Hypersensitivity to any of the active ingredients or excipients.
  • Patients with glaucoma, pheochromocytoma, epileptic disease, Parkinson's disease and other established extrapyramidal disorders or in the course of anticholinergic therapy.
  • Cases in which the stimulation of intestinal motility can be dangerous, for example in the presence of gastrointestinal bleeding, perforation, mechanical obstruction.
  • Patients with Porphyria.
  • Children under the age of 16.
  • Pregnancy and breastfeeding.

Warnings Geffer Effervescent Granules 24 Sachets 5 g

Avoid concomitant administration of neuroleptics – phenothiazines, butyrophenones, thioxanthenes, etc. – sedatives and alcohol. The use of the product can give rise to disturbances such as to alter the normal state of vigilance; this should be taken into account by patients engaged in driving motor vehicles or in operating potentially dangerous machinery. After a maximum of 3 days of treatment without appreciable results, consult your doctor. Elderly patients should not exceed 3 days of consecutive treatment and should comply with the minimum dosages indicated. One Geffer sachet contains 287 mg (12.5 mmol) of sodium: this should be taken into account in case of hypertension and in all situations requiring a controlled sodium intake (patients with congestive heart failure, renal failure, nephrotic syndrome, etc.). The product contains sucrose, therefore patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicinal product. The sucrose content is 2.95 g per sachet: this must be taken into account in case of diabetes or low-calorie diets.

Interactions Geffer Effervescent Granules and other Drugs:
The sedative effects of metoclopramide are enhanced by alcohol. Anticholinergics and morphine derivatives antagonize the effect of metoclopramide on intestinal motility. The sedative effects of CNS depressants (morphine derivatives, sleep inducers, anxiolytics, sedative antihistamines, sedative antidepressants, barbiturates, etc.) and metoclopramide are potentiated. The combination of metoclopramide with drugs inducing extrapyramidal effects such as phenothiazines, butyrophenones and thioxanthenes should be avoided (in particular, the activity of phenothiazines is increased, regardless of the appearance or enhancement of the extrapyramidal effects) Increases the effects of MAOIs, sympathomimetics, tricyclic antidepressants. Due to the prokinetic effect of metoclopramide, the absorption of some drugs may be impaired. Metoclopramide may reduce the bioavailability of digoxin, while it increases the bioavailability of cyclosporine. Reduces the CNS effects of apomorphine. It reduces the bioavailability of cimetidine by an average of about 22%, without, however, having any clinically relevant consequences. Metoclopramide interacts with serotonergic drugs (e.g. selective serotonin reuptake inhibitors), increasing the risk of serotonin syndrome.

Side effects Geffer Effervescent Granules 24 Sachets 5 g

Following the use of Geffer Effervescent Granules, the undesirable effects listed below may occur rarely (frequency < 1/1000).

  • Systemic effects: Fatigue Endocrine and metabolic effects. Hypertensive crises, sometimes with a fatal outcome, have been reported in patients with pheochromocytoma; therefore, the use of Geffer is contraindicated in these patients. Following the use of the product, in relation to the prolactin-producing activity of metoclopramide, the following may occur: hyperprolactinaemia, menstrual cycle disorders, galactorrhea and gynaecomastia in men.
  • Effects on the nervous system: Drowsiness, fatigue, dizziness and extrapyramidal reactions of various types, usually of the dystonic type, have been reported with the use of metoclopramide. They may include facial twitching, trismus, extra-ocular muscle spasms with oculogyric crises, abnormal head positions; these reactions usually subside within 24 hours of stopping treatment. The development of potentially irreversible tardive dyskinesia has been reported in some elderly patients treated for prolonged periods; therefore, in elderly patients, therapies lasting more than 3 days should be absolutely avoided.
  • Effects on Metabolism and Nutrition: Cases of porphyria have been reported Reporting of suspected adverse reactions.

Overdose Geffer Effervescent Granules:
Metoclopramide can induce reactions of neurodystonic type, somnolence, disorientation, especially at plasma levels > 100 ng/ml. Dyskinesias responding to treatment with diazepam or anticholinergics may occur. Prolonged use of metoclopramide can also cause galactorrhea and amenorrhea, linked to the stimulation of prolactin secretion.

Pregnancy and breastfeeding Geffer Effervescent Granules 24 Sachets 5 g

Can I take Geffer Effervescent Granules when pregnant or breastfeeding?

The product should not be used during pregnancy and breastfeeding.

Expiration and conservation of Geffer Effervescent Granules 24 Sachets 5 g

How to store Geffer Effervescent Granules?

Storage: Store at a temperature not exceeding 25°C



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