Hyalubrix 30 mg/2 ml syringes 3 pieces intra-articular

Hyalubrix 30 mg/2 ml 3-piece intra-articular syringes is a sterile, viscoelastic solution based on high molecular weight hyaluronic acid sodium salt , obtained through bacterial fermentation. This product is intended for the temporary replacement of synovial fluid in joints, making it particularly suitable for patients with degenerative or mechanical arthropathy who experience reduced synovial fluid viscosity and symptoms of persistent joint pain .

Hyaluronic acid, the main component of Hyalubrix, is a polysaccharide naturally present in human cartilage and synovial fluid, where it plays a fundamental role in ensuring viscosity, elasticity, and lubrication of joints. In pathological conditions, its concentration decreases, compromising joint function and increasing the risk of mechanical damage to cartilage and soft tissue. Intra-articular injection of Hyalubrix restores the viscoelastic properties of synovial fluid , improving joint function and reducing pain for up to six months.

The package contains three pre-filled syringes of 2 ml each, each providing 30 mg of hyaluronic acid sodium salt in a steam-sterilized solution. The product is intended exclusively for intra-articular injections performed by specialized medical personnel, such as orthopedists, rheumatologists, or physiatrists. Hyalubrix is ​​ideal for the treatment of joints affected by degenerative processes or trauma, offering effective support for joint health and mobility.

The Hyalubrix formulation is complemented by sodium chloride, dibasic sodium phosphate, monobasic sodium phosphate, and water for injections , ensuring maximum purity and safety. The product is sterilized by moist heat and packaged in sealed blisters to preserve integrity and sterility until use.

Choosing Hyalubrix 30 mg/2 ml 3-piece intra-articular syringes means relying on an advanced solution for the treatment of joint pain and the improvement of joint function , with the quality guarantee of Fidia, a leading company in the sector of medical devices for joint health.

Hyalubrix 30 mg/2 ml 3-piece intra-articular syringes is a sterile, viscoelastic solution based on hyaluronic acid sodium salt, indicated for the temporary replacement of synovial fluid in patients with degenerative or mechanical arthropathy. Intra-articular injection of Hyalubrix reduces pain symptoms and improves joint function for up to six months.

Dosage and method of use

How do I use Hyalubrix 30 mg/2 ml 3-piece intra-articular syringes?

Intended for intra-articular injection only. The product should be administered exclusively by specialized physicians (e.g., orthopedic surgeon, rheumatologist, physiatrist, sports physician, etc.). The injection must be strictly intra-articular. The intra-articular injection must be performed according to the standard technique, using precise anatomical localization. In the hip, shoulder, and other less easily accessible joints, ultrasound or radioscopic guidance is recommended. All rules regarding asepsis and injection techniques must be observed. Remove any joint effusions, if present, before administration. Attach a suitable sterile needle to the syringe (e.g., 18 or 20 gauge) and inject HYALUBRIX into the affected joint at weekly intervals for 3 weeks. If necessary, additional injection cycles may be performed, although systematic collection of clinical data is not available. Clinical data demonstrate the efficacy of HYALUBRIX for up to 6 months, however, if clinically required, the administration cycle can be repeated starting 3 months after the first treatment cycle.

Average analysis Hyalubrix 30 mg/2 ml syringes 3 pieces intra-articular

What does Hyalubrix 30 mg/2 ml 3-piece intra-articular syringe contain?

Main component: hyaluronic acid sodium salt 1.5%. Other components: sodium chloride, dibasic sodium phosphate 12H ₂ O, monobasic sodium phosphate 2H ₂ O, water for injections.

Ingredients Hyalubrix 30 mg/2 ml syringes 3 pieces intra-articular

What ingredients does Hyalubrix 30 mg/2 ml 3-piece intra-articular syringe contain?

Hyaluronic acid sodium salt 1.5%, sodium chloride, dibasic sodium phosphate 12H ₂ O, monobasic sodium phosphate 2H ₂ O, water for injections.

Warnings

What are the warnings for Hyalubrix 30 mg/2 ml 3-piece intra-articular syringes?

Do not administer to patients with known individual sensitivity to the product components. Do not administer in case of infections or skin diseases in the injection area. Do not administer to patients with active synovitis. The safety and efficacy of HYALUBRIX in pregnant women, breastfeeding women, or individuals under 18 years of age have not been established and therefore its use is contraindicated in these patient populations. Do not use if the package is damaged. Do not use the product after the expiry date shown on the package. The expiry date refers to the product stored in its original packaging. The syringe is for single use only, meaning it is for single use only and on a single patient. Inject the contents into one joint only. For the first 24 hours after the injection, the patient is permitted to continue all routine daily activities, but it is recommended not to overload the treated joint. The syringe complete with needle must be discarded immediately after use, even if the solution has not been completely administered. If the product is reprocessed and/or reused, Fidia Farmaceutici cannot guarantee its performance, functionality, material structure, cleanliness, or sterility. Reuse may lead to illness, infection, and/or harm to the patient or user. After use, dispose of according to applicable regulations. Keep out of reach of children. Localized pain, swelling, heat, and redness may occasionally occur at the injection site. These symptoms are generally mild and transient. After intra-articular injection, applying an ice pack to the treated joint for five to ten minutes will reduce the incidence of these events. Local or systemic allergic reactions may occur in individuals with hypersensitivity to the product's components. More marked inflammatory reactions, sometimes with the presence of sodium pyrophosphate crystals, have occasionally been reported in conjunction with intra-articular hyaluronate injections. As with any intra-articular treatment, septic arthritis may rarely occur if general injection precautions are not observed or the injection site is not aseptic. Do not use concomitantly with disinfectants containing quaternary ammonium salts, as hyaluronic acid may precipitate in their presence. Avoid concomitant administration of HYALUBRIX with other intra-articular products to prevent any possible interactions.

Hyalubrix 30 mg/2 ml syringes 3 intra-articular pieces format

Case containing 3 pre-filled syringes. The syringe is sealed in an ethylene oxide sterilized blister and contains 30 mg of hyaluronic acid sodium salt in 2 ml of steam-sterilized solution.