Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g

Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g it's a medical device ad laxative action in 30 disposable sachets: each contains 10 g of macrogol 4000 and nothing else, because the formula does not have excipients, has no aromas and no sugars. It is used in chronic constipation and in cases of occasionally irregular bowel, and it is a macrogol without electrolytes, which distinguishes it from most products of the same family.

The macrogol 4000 it is the only substance present, and it is worth knowing what that number means, because almost everyone reads it as a dosage and it is not. Macrogol is the name that the European Pharmacopoeia gives to polyethylene glycol, a polymer made of repeating units; the following number indicates the average molecular weight of the espresso chain in dalton. Macrogol 4000 therefore means chains on average 4,000 daltons long: a large molecule, and the size is precisely the reason why it works the way it does. I 10 g of the sachet they are instead the quantity of substance, and they are the whole sachet.

The way he acts is physical, non-pharmacological, and you can feel the difference. Water molecules bind to the polymer to hydrogen bond even before it reaches the intestine, and they remain attached: in the intestinal lumen the retained water increases the volume of the stool and softens its consistency. A osmotic laxative as this does not affect the nerve plexuses of the wall or the muscles, which is what laxatives do instead stimulants or contact. The chain is too large to cross the mucosa, therefore it is not absorbed, and is not a substrate for colon bacteria, therefore it doesn't ferment: it is the reason why it does not produce the gas that accompanies sugar osmotics such as lactulose. Macrogol 4000 is useful in cases of chronic constipation and occasionally irregular bowel movements.

The word without electrolytes deserves its own line, because two different things with the same name coexist in the department. Different macrogols are formulated together with go up (sodium, potassium, bicarbonate, chloride) which serve to maintain the balance of electrolytes when drinking a lot of liquid in one go: these are preparations designed for large volumes. Clin 4000 it doesn't contain them: it just carries the polymer, and for this reason the powder doesn't have the salty taste that macrogols with electrolytes carry with them. It is also without aroma, and this is not a shortcoming but the reason why it can be combined with any drink, from tea to broth to fruit juice, without changing its taste.

Clin 4000 it's a medical device in 30 disposable sachets, for 300 g total of macrogol 4000: the single-dose sachet avoids having to weigh the powder and the single wrapper remains closed until needed. The formula is sugar free, which matters to those keeping carbs under control, and it has no added excipients. In the same line there is the 200 g bottle with measuring spoon, the format that allows divided doses and is the one aimed at younger children: the MINSAN it looks a lot like the one in the sachets, so it's worth looking carefully at which one you're taking. Those looking for a pure macrogol, without salts and without flavourings, will find it in Clin 4000 the most essential form.

INDICATIONS

Why should you use Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g? What is it for?

Clin 4000 it's a medical device ad laxative action in 30 disposable sachets, each with 10 g of macrogol 4000.

It is used in chronic constipation and in cases of occasionally irregular bowel.

The macrogol 4000 it's a osmotic laxative: retains water in the intestinal lumen and makes stool softer.

INGREDIENTS

What ingredients does Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g contain?

Macrogol 4000.

Each sachet contains 10 g of macrogol 4000. It contains no excipients or flavourings. Without sugar.

HOW TO USE

How do I use Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g?

Dissolve the powder by mixing in any drink. The contents of one sachet (10 g) must be dissolved in at least 125ml (increase to 150 ml in pediatric age) of any drink, even hot, such as tea, herbal teas, milk, broth or fruit juice. The product does not alter the taste of the drink. Drink the reconstituted solution. It is recommended to take between meals.

Due to its safety features, it allows for wide dosing flexibility.

Adults and children weighing more than 20 kg: 10 g (1 sachet), 1-3 times a day, according to individual response. To obtain a faster effect, the maximum daily dose (30 g) can be taken in a single administration. In case of prolonged use, the dose can be reduced to 10 g (1 sachet) 1-2 times a day, even every other day, preferably in the evening.

Children up to 20 kg: the dosage should be commensurate with body weight. We therefore recommend using the 200 g bottle of powder with measuring spoon, which allows you to customize the dose according to the child's real needs until soft stools are obtained. Do not exceed the maximum daily dosage of 30 g.

WARNINGS

What are the warnings of Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g?

Do not take in case of: known hypersensitivity to macrogol; gastrointestinal perforation and/or obstruction.

During pregnancy and breastfeeding the product must be used upon medical prescription.

There are no known interactions with drugs, but it is advisable to take the product at least 2 hours apart from that of oral drugs.

Occasionally abdominal distension and/or nausea may be noted, which resolve with continued use. Rare cases of allergic reactions (rash, urticaria): in this case, suspend use of the product and inform your doctor or pharmacist.

In case of overdose, diarrhea may occur, which resolves spontaneously upon discontinuation of the product.

CONSERVATION

How is Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g stored?

Store in the original packaging cool and dry place. The expiry date indicated refers to the product in intact packaging and correctly stored.

The manufacturer also declares, in the European registration of the device, to maintain the product below 25 °C, in a dry place and away from direct sources of heat or light.

FORMAT

What is the format of Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g?

30 sachets of 10 g.