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FIDIA FARMACEUTICI SpA

Connettivina Plus 0, 2 % + 1 % 25 g cream

Connettivina Plus 0, 2 % + 1 % 25 g cream

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Connettivina Plus 0.2% + 1% cream 25 g is a topical healing cream indicated for the treatment of wounds , first and second degree burns , bedsores, ulcers and skin irritations. Thanks to hyaluronic acid and silver sulfadiazine , it promotes tissue regeneration , keeps the wound moist, prevents skin infections and supports rapid and safe healing even on sensitive skin.

NET WEIGHT OF THE PRODUCT

EAN

028440030

MINSAN

028440030

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Connettivina Plus 0.2% + 1% 25 g cream is a dermatological cream for topical use, formulated for the local treatment of wounds, first and second degree burns, bedsores, ulcers and skin irritations . Its unique composition combines hyaluronic acid (sodium salt) and silver sulfadiazine , two active ingredients known for their healing, regenerating and antibacterial properties. Hyaluronic acid promotes tissue regeneration and maintains an optimal moist environment for wound healing , while silver sulfadiazine has an antimicrobial action, preventing skin infections and promoting rapid healing.

This healing cream is indicated for the prophylaxis and local treatment of skin lesions of various kinds, helping to reduce the risk of infections and speed up the healing process. Thanks to its delicate texture, Connettivina Plus is easy to apply and quickly absorbed, making it ideal even for the most sensitive skin. The 25 g format is practical and suitable for both home use and for application in the healthcare sector. Choose Connettivina Plus for effective and safe wound care , with the guarantee of a high-quality medical device designed for the well-being of your skin.


ACTIVE INGREDIENTS

Active ingredients contained in Connettivina Plus 0.2% + 1% 25 g cream - What is the active ingredient of Connettivina Plus 0.2% + 1% 25 g cream?

CONNETTIVINA PLUS 2 mg/g + 10 mg/g cream 1 g of cream contains 2 mg of Hyaluronic acid sodium salt and 10 mg of Silver sulfadiazine. CONNETTIVINA PLUS 2 mg + 40 mg impregnated gauzes Each 10x10 cm gauze is impregnated with 4 g of cream containing 2 mg of Hyaluronic acid sodium salt and 40 mg of Silver sulfadiazine. CONNETTIVINA PLUS 4 mg + 80 mg impregnated gauzes Each 10x20 cm gauze is impregnated with 8 g of cream containing 4 mg of Hyaluronic acid sodium salt and 80 mg of Silver sulfadiazine. CONNETTIVINA PLUS 12 mg + 240 mg impregnated gauze Each 20x30 cm gauze is impregnated with 24 g of cream containing 12 mg of hyaluronic acid sodium salt and 240 mg of silver sulfadiazine. For the full list of excipients, see section 6.1.

EXCIPIENTS

Composition of Connettivina Plus 0.2% + 1% 25 g cream - What does Connettivina Plus 0.2% + 1% 25 g cream contain?

CONNETTIVINA PLUS 2 mg/g + 10 mg/g cream Polyethylene glycol 400 monostearate – oleic acid decyl ester – emulsifying wax – glycerol – sorbitol solution 70% – purified water CONNETTIVINA PLUS 2 mg + 40 mg impregnated gauzes CONNETTIVINA PLUS 4 mg + 80 mg impregnated gauzes CONNETTIVINA PLUS 12 mg + 240 mg impregnated gauzes Polyethylene glycol 4000 – glycerol – purified water

DIRECTIONS

Therapeutic indications Connettivina Plus 0.2% + 1% 25 g cream - Why is Connettivina Plus 0.2% + 1% 25 g cream used? What is it used for?

Local treatment of mild wounds Local treatment of first and second degree burns

CONTRAINDICATIONS AND SIDE EFFECTS

Contraindications Connettivina Plus 0.2% + 1% 25 g cream - When should Connettivina Plus 0.2% + 1% 25 g cream not be used?

Hypersensitivity to the active substances and other closely related chemical substances or to any of the excipients listed in paragraph 6.1.

DOSAGE

Quantity and method of taking Connettivina Plus 0.2% + 1% 25 g cream - How to take Connettivina Plus 0.2% + 1% 25 g cream?

CONNETTIVINA PLUS 2 mg/g + 10 mg/g cream : spread a uniform layer of cream 2–3 mm thick over the entire lesion site, once or twice a day. CONNETTIVINA PLUS 2 mg + 40 mg impregnated gauzes CONNETTIVINA PLUS 4 mg + 80 mg impregnated gauzes CONNETTIVINA PLUS 12 mg + 240 mg impregnated gauzes : Apply one or more medicated gauzes two or more times a day depending on the extent of the lesions. Before applying CONNETTIVINA PLUS, the affected areas must be cleaned preferably with sterile saline solution (0.9% NaCl) and disinfected with antiseptics preferably containing povidone-iodine or chlorhexidine. If necessary, surgical cleaning must be performed. In the treatment of burns, cleaning of the lesions is preferable to be done with only water or sterile saline solution, avoiding disinfection with antiseptic agents before applying Connettivina PLUS cream or impregnated gauze. After cleansing the injured parts, spread a uniform layer of cream 2 or 3 mm thick or apply the impregnated gauze. The application must continue as long as there is a possibility of infection and until complete healing.

CONSERVATION

Storage Connettivina Plus 0.2% + 1% 25 g cream - How do you store Connettivina Plus 0.2% + 1% 25 g cream?

Store below 30°C.

WARNINGS

Warnings Connettivina Plus 0.2% + 1% 25 g cream - About Connettivina Plus 0.2% + 1% 25 g cream it is important to know that:

CONNETTIVINA PLUS must be used with caution in subjects who have shown previous allergies to sulphonamides and in the presence of hepatic or renal insufficiency.

INTERACTIONS

Interactions Connettivina Plus 0.2% + 1% 25 g cream - Which medicines or foods can modify the effect of Connettivina Plus 0.2% + 1% 25 g cream?

Local proteolytic enzymes, applied simultaneously with CONNETTIVINA PLUS, can be inactivated by the presence of silver ions. Do not use simultaneously with disinfectants containing quaternary ammonium salts since hyaluronic acid can precipitate in their presence.

SIDE EFFECTS

Like all medicines, Connettivina Plus 0.2% + 1% 25 g cream can cause side effects - What are the side effects of Connettivina Plus 0.2% + 1% 25 g cream?

After the application of CONNETTIVINA PLUS, local reactions (pain, burning, itching) may occur, including allergic reactions. Since the systemic administration of sulphonamides can cause adverse reactions such as renal failure, toxic hepatitis, agranulocytosis, thrombocytopenia and leukopenia, it cannot be excluded that the local treatment of large parts of the body with CONNETTIVINA PLUS may give rise to side effects typical of sulphonamides administered systemically. Reporting of suspected adverse reactions Reporting suspected adverse reactions that occur after authorisation of the medicinal product is important, as it allows continuous monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at www.agenziafarmaco.gov.it/it/responsabili.

OVERDOSE

Overdose Connettivina Plus 0.2% + 1% 25 g cream - What are the risks of Connettivina Plus 0.2% + 1% 25 g cream in case of overdose?

There are no known cases of overdose.

PREGNANCY AND BREASTFEEDING

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking Connettivina Plus 0.2% + 1% 25 g cream.

In the absence of data on the effects of the medicinal product on the fetus, CONNETTIVINA PLUS should not be used during pregnancy and breastfeeding unless the doctor considers that the therapeutic benefits outweigh the possible risks.

DRIVING AND USE OF MACHINERY

Take Connettivina Plus 0.2% + 1% 25 g cream before driving or using machines - Does Connettivina Plus 0.2% + 1% 25 g cream affect driving or using machines?

CONNETTIVINA PLUS does not alter the ability to drive vehicles or use machinery.
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