
Progepril 28 tablets is a medication containing micronized natural progesterone , used in gynecology to treat various conditions related to hormonal imbalance. It is primarily used for menstrual cycle disorders, amenorrhea, premenstrual syndrome, mastalgia, and as part of hormone replacement therapy (HRT) during menopause. Each tablet contains 100 mg of progesterone and works by mimicking the action of endogenous progesterone produced by the corpus luteum, helping restore normal female hormonal balance.
Directions
When is Progepril indicated?
Progepril is indicated in all clinical situations requiring exogenous progesterone supplementation. In particular, it is indicated in the following cases:
- Menstrual cycle disorders : irregularity, dysmenorrhea, anovulatory cycles;
- Secondary amenorrhea (in the absence of pregnancy);
- Premenstrual syndrome with neurovegetative and affective symptoms;
- Mastodynia (cyclical breast pain);
- As part of hormone replacement therapy (HRT) in menopausal women with an intact uterus, in combination with estrogens;
- Threatened or recurrent miscarriages due to luteal deficiency (only under strict medical supervision);
- Luteal phase support in medically assisted reproduction techniques (MAP).
Dosage and method of use
How do I take Progepril?
The dosage of Progepril depends on the clinical condition being treated and the individual response. Generally:
- Menstrual cycle disorders : 1 100 mg tablet 1 or 2 times a day from the 14th to the 25th day of the cycle;
- Amenorrhea : after adequate estrogen treatment, 1 100 mg tablet for 10 days;
- Premenstrual syndrome and mastalgia : 100 mg daily in the 10-12 days preceding menstrual flow;
- Hormone replacement therapy : 1 tablet of 100-200 mg/day for 12-14 days a month, combined with estrogen;
- Support in assisted reproduction : according to medical protocol, up to 600 mg per day in 2-3 administrations.
The tablets should be taken orally with water, preferably on an empty stomach. Always follow your doctor's instructions.
Contraindications
What are the main contraindications of Progepril?
Progepril is contraindicated in the following cases:
- Hypersensitivity to the active substance (progesterone) or to any of the excipients;
- Undiagnosed vaginal bleeding;
- Hormone-dependent tumors (e.g. known or suspected breast cancer);
- Thrombophlebitis, deep vein thrombosis, pulmonary embolism, or a history of these conditions;
- Severe liver failure;
- Confirmed or suspected pregnancy, unless explicitly indicated by a doctor;
- Breastfeeding (progesterone is excreted in breast milk).
Side effects
What are the side effects of Progepril?
Like all medicines, Progepril can cause side effects, although not all patients experience them. Among the most common are:
- Dizziness, drowsiness, fatigue;
- Headache, nausea, feeling of heaviness in the stomach;
- Mood swings, irritability;
- Breast tenderness, spotting between periods;
- Changes in the menstrual cycle (delays, advances);
- In rare cases: cholestatic jaundice, itching, weight gain, acne.
In case of severe or suspected side effects, discontinue treatment and consult your doctor immediately.
Warnings
What are the warnings for Progepril?
It is important to take Progepril under medical supervision, especially:
- During prolonged treatments it is necessary to monitor liver function;
- May cause drowsiness: be careful when driving or operating machinery;
- If jaundice, severe headache or blurred vision occurs, discontinue treatment;
- Always inform your doctor if you have any cardiovascular diseases or previous thrombotic episodes;
- Do not use as a contraceptive;
- Interactions: May interfere with some drugs such as antiepileptics, barbiturates and rifampicin.
Expiration and storage
What are the expiration dates and storage times for Progepril?
Store the medicine below 25°C in the original package to protect from light and moisture.
Expiration date: shown on the package. Do not use after the date shown. Do not dispose of in the environment.
Format
Pack of 28 tablets of 100 mg of micronized progesterone.
Progepril is a prescription-only drug. Available at Tili Pharmacy with fast and discreet shipping.








