Daflon 500 mg 120 coated tablets

Daflon 500 mg 120 coated tablets is a reference vasoprotector , indicated for the treatment of venous circulation disorders such as venous insufficiency , capillary fragility and for the symptomatic treatment of haemorrhoidal crises . Each tablet contains a micronized purified flavonoid fraction composed of 450 mg of diosmin and 50 mg of flavonoids expressed in hesperidin , active ingredients known for their beneficial action on blood circulation and microcirculation .

Thanks to its formulation, Daflon 500 mg helps strengthen the walls of veins and capillaries , reducing the feeling of heaviness and swelling in the legs, typical of venous insufficiency. It is also particularly useful in the case of hemorrhoids , helping to reduce the symptoms of the hemorrhoid crisis and promoting the well-being of the anal area. The coated tablets are easy to take and well tolerated, ideal for prolonged treatments and for those who need effective protection of veins and capillaries .

Daflon 500 mg 120 tablets is the ideal choice for those seeking a complete and reliable treatment for the health of the venous system , thanks to the synergistic action of flavonoids and diosmin . The 120-tablet format guarantees prolonged coverage, particularly suitable for those suffering from chronic circulatory disorders or requiring continuous support for microcirculation .

ACTIVE INGREDIENTS

Active ingredients contained in Daflon 500 mg 120 coated tablets - What is the active ingredient in Daflon 500 mg 120 coated tablets?

Each film-coated tablet contains 500 mg of micronized purified flavonoid fraction consisting of 450 mg of diosmin and 50 mg of flavonoids expressed as hesperidin. For the full list of excipients, see section 6.1.

EXCIPIENTS

Composition of Daflon 500 mg 120 coated tablets - What does Daflon 500 mg 120 coated tablets contain?

Sodium starch glycolate, microcrystalline cellulose, gelatin, glycerin, hypromellose, sodium lauryl sulphate, yellow iron oxide E172, red iron oxide E172, titanium dioxide, macrogol 6000, magnesium stearate, talc.

DIRECTIONS

Therapeutic indications Daflon 500 mg 120 coated tablets - Why is Daflon 500 mg 120 coated tablets used? What is it used for?

Symptoms attributable to venous insufficiency; states of capillary fragility. Symptomatic treatment of acute hemorrhoidal crisis.

CONTRAINDICATIONS AND SIDE EFFECTS

Contraindications Daflon 500 mg 120 coated tablets - When should Daflon 500 mg 120 coated tablets not be used?

Hypersensitivity to the active substance or to any of the excipients listed in paragraph 6.1.

DOSAGE

Quantity and method of taking Daflon 500 mg 120 coated tablets - How to take Daflon 500 mg 120 coated tablets?

Dosage Venous insufficiency (including haemorrhoidal plexus) and capillary fragility The recommended dose is 2 tablets to be taken in two administrations per day. Do not exceed the maximum daily dose. Acute haemorrhoidal crisis The recommended dose is 3 tablets twice a day during the first 4 days of treatment; in the following 3 days the daily dose is 4 tablets in two administrations. Do not exceed the maximum daily dose. Method of administration Take the tablets with the two main meals. Duration of treatment The treatment should not be continued beyond 7 days. In the absence of a therapeutic response, reassess the situation.

CONSERVATION

Storage Daflon 500 mg 120 coated tablets - How to store Daflon 500 mg 120 coated tablets?

This medicinal product does not require any special storage conditions.

WARNINGS

Warnings Daflon 500 mg 120 coated tablets - About Daflon 500 mg 120 coated tablets it is important to know that:

Important information about some of the excipients Daflon contains less than 1 mmol (23 mg) sodium per tablet, that is to say essentially 'sodium-free'.

INTERACTIONS

Interactions Daflon 500 mg 120 coated tablets - Which medicines or foods can modify the effect of Daflon 500 mg 120 coated tablets?

No interaction studies have been performed. No clinically relevant drug interactions have been reported so far from post-marketing experience with the product.

SIDE EFFECTS

Like all medicines, Daflon 500 mg 120 coated tablets can cause side effects - What are the side effects of Daflon 500 mg 120 coated tablets?

The following adverse reactions or effects have been reported and have been classified according to the following frequency: very common (≥1/10); common (≥1/100, <1/10); uncommon (≥1/1,000, <1/100); rare (≥1/10,000, <1/1,000); very rare (<1/10,000), not known (cannot be estimated from the available data). Nervous system disorders Rare: dizziness, headache, malaise Gastrointestinal disorders Common: diarrhoea, dyspepsia, nausea, vomiting Uncommon: colitis Not known: abdominal pain Skin and subcutaneous tissue disorders Rare: rash, pruritus, urticaria Not known: oedema of the face, lips, eyelid; Quincke's edema Blood and lymphatic system disorders Not known: thrombocytopenia Reporting of suspected adverse reactions Reporting suspected adverse reactions that occur after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at https://www.aifa.gov.it/content/segnalazioni-reazioni-avverse.

OVERDOSE

Overdose Daflon 500 mg 120 coated tablets - What are the risks of Daflon 500 mg 120 coated tablets in case of overdose?

Symptoms There is limited experience with overdose of Daflon. The most frequently reported adverse events in overdose cases were gastrointestinal events (such as diarrhea, nausea, abdominal pain) and skin events (such as pruritus, rash). Management Management of overdose should consist of treatment of clinical symptoms.

PREGNANCY AND BREASTFEEDING

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking Daflon 500 mg 120 coated tablets.

Pregnancy There are no or limited amount of data from the use of micronized purified flavonoid fraction in pregnant women. Animal studies do not indicate reproductive toxicity (see section 5.3). As a precautionary measure, it is preferable to avoid the use of Daflon during pregnancy. Breast- feeding It is not known whether the active substance/metabolites are excreted in human milk. A risk to the newborns/infants cannot be excluded. A decision must be made whether to discontinue breast-feeding or to discontinue/abstain from therapy with Daflon taking into account the benefit of breast-feeding for the child and the benefit of therapy for the woman. Fertility Reproductive toxicity studies have shown no effect on fertility in either male or female rats (see section 5.3).

DRIVING AND USE OF MACHINERY

Taking Daflon 500 mg 120 coated tablets before driving or using machines - Does Daflon 500 mg 120 coated tablets affect driving or using machines?

No studies have been conducted to evaluate the effect of the flavonoid fraction on the ability to drive or use machines.