Calcium Sandoz 500 mg 20 effervescent tablets

Calcium Sandoz 500 mg 20 effervescent tablets is a calcium supplement formulated to support the daily requirement of this essential mineral, fundamental for the health of bones and teeth. Thanks to its composition based on calcium lactate gluconate and calcium carbonate , the product guarantees an optimal calcium intake, making it particularly suitable for the prevention and treatment of calcium deficiency in both adults and children. The effervescent tablets are easy to take: just dissolve them in water to obtain a pleasant-tasting drink, also ideal for those who have difficulty swallowing traditional tablets.

Calcium Sandoz 500 mg is the ideal solution for those who need an effective calcium supplement , both in case of nutritional deficiencies and to support bone health during growth, pregnancy, breastfeeding or old age. The pack of 20 effervescent tablets is practical and suitable for daily use, offering valid support for the well-being of the body. Choose Calcium Sandoz 500 mg for a safe, reliable calcium supply with guaranteed quality from Sandoz .

ACTIVE INGREDIENTS

Active ingredients contained in Calcium Sandoz 500 mg 20 effervescent tablets - What is the active ingredient of Calcium Sandoz 500 mg 20 effervescent tablets?

Each 500 mg effervescent tablet contains : 1,132 mg calcium lactate gluconate and 875 mg calcium carbonate (equivalent to 500 mg or 12.5 mmol calcium). Excipients with known effect: Each 500 mg effervescent tablet contains, 30 mg of aspartame (E 951), 68.45 mg sodium (2.98 mmol), 30 mg orange flavour powder (containing 630 micrograms sorbitol (E 420), 180 nanograms benzyl alcohol, 210 nanograms sulphur dioxide (E 220) and 13.08 mg glucose). Each 1,000 mg effervescent tablet contains : 2,263 mg calcium lactate gluconate and 1,750 mg calcium carbonate (equivalent to 1,000 mg or 25 mmol calcium). Excipients with known effect: Each 1,000 mg effervescent tablet contains 30 mg aspartame (E 951), 136.90 mg sodium (5.95 nmol), 30 mg orange flavour powder (containing 630 micrograms sorbitol (E 420), 180 nanograms benzyl alcohol, 210 nanograms sulphur dioxide (E220) and 13.08 mg glucose). For the full list of excipients, see section 6.1.

EXCIPIENTS

Composition of Calcium Sandoz 500 mg 20 effervescent tablets - What does Calcium Sandoz 500 mg 20 effervescent tablets contain?

Citric acid anhydrous (fine granules); Orange flavour powder (contains: benzyl alcohol, sorbitol (E 420), glucose and sulphur dioxide (E 220)); Aspartame (E951); Macrogol 6000; Sodium bicarbonate.

DIRECTIONS

Therapeutic indications Calcium Sandoz 500 mg 20 effervescent tablets - Why is Calcium Sandoz 500 mg 20 effervescent tablets used? What is it used for?

- Prevention and treatment of calcium deficiency. - Calcium supplementation as a supplement to specific therapy in the prevention and treatment of osteoporosis. - Rickets and osteomalacia, in addition to vitamin D3 therapy.

CONTRAINDICATIONS AND SIDE EFFECTS

Contraindications Calcium Sandoz 500 mg 20 effervescent tablets - When should Calcium Sandoz 500 mg 20 effervescent tablets not be used?

- Hypersensitivity to the active substances or to any of the excipients listed in paragraph 6.1 of the effervescent tablet. - Pathologies and/or conditions leading to hypercalcaemia and/or hypercalciuria. - Nephrocalcinosis, nephrolithiasis.

DOSAGE

Quantity and method of taking Calcium Sandoz 500 mg 20 effervescent tablets - How to take Calcium Sandoz 500 mg 20 effervescent tablets?

Adults: 500 - 1,500 mg daily. Children: 500 - 1,000 mg daily. The effervescent tablets should be dissolved in a glass of water (approximately 200 ml) and the resulting solution drunk immediately. Calcium Sandoz effervescent tablet can be taken with or without food.

CONSERVATION

Storage Calcium Sandoz 500 mg 20 effervescent tablets - How to store Calcium Sandoz 500 mg 20 effervescent tablets?

Keep tube tightly closed. Store in original package.

WARNINGS

Warnings Calcium Sandoz 500 mg 20 effervescent tablets - About Calcium Sandoz 500 mg 20 effervescent tablets it is important to know that:

In patients with mild hypercalciuria (over 300 mg/24 hours or 7.5 mmol/24 hours), or with a history of urinary calculi, monitoring of urinary calcium excretion is required. If necessary, the calcium dose should be reduced or therapy should be discontinued. Increased fluid intake is recommended in patients predisposed to urinary tract stone formation. In patients with impaired renal function, calcium salts should be taken under medical supervision with monitoring of serum calcium and phosphate levels. During high-dose therapy and especially in case of concomitant treatment with vitamin D, there is a risk of hypercalcaemia with consequent impairment of renal function. In these patients, serum calcium levels should be monitored and renal function should be monitored. There have been reports in the literature of a possible increase in aluminium absorption with citrate salts. Calcium Sandoz effervescent tablet (containing 1662.00 mg (500 mg tablets) or 3323.0 mg (1000 mg tablets) of citric acid) should be used with caution in patients with severely impaired renal function, especially in those also taking preparations containing aluminium. This medicinal product contains aspartame, sodium, sorbitol, benzyl alcohol, sulphur dioxide and glucose . This medicinal product contains 630 micrograms of sorbitol (E 420) per tablet. This medicinal product contains 2.98 mmol (corresponding to 68.45 mg) sodium per effervescent tablet, equivalent to 3.4% of the WHO recommended maximum daily intake of 2 g sodium for an adult. This medicinal product contains 180 nanograms of benzyl alcohol in each tablet. Benzyl alcohol may cause allergic reactions. Intravenous administration of benzyl alcohol has been associated with serious adverse events and death in neonates (agonal breathing syndrome). The minimum amount of benzyl alcohol that causes toxicity is unknown. Increased risk due to accumulation in young children. High volumes should be used with caution and only if necessary, especially in pregnant or breast-feeding patients and in subjects with hepatic or renal insufficiency due to the risk of accumulation and toxicity (metabolic acidosis). This medicinal product contains 210 nanograms of sulphur dioxide which may rarely cause severe hypersensitivity reactions and bronchospasm. This medicinal product contains 30 mg of aspartame in each effervescent tablet. Aspartame is a source of phenylalanine and may be harmful to people with phenylketonuria. This medicinal product contains glucose. Patients with rare glucose-galactose malabsorption problems should not take this medicine. It may also be harmful to teeth. Calcium Sandoz 1000 mg contains aspartame, sodium, sorbitol, benzyl alcohol, sulphur dioxide and glucose. This medicinal product contains 630 micrograms of sorbitol (E 420) in each tablet. This medicinal product contains 5.95 mmol (corresponding to 136.90 mg) sodium per tablet equivalent to 6.9% of the WHO recommended maximum daily intake of 2 g sodium for an adult. This medicinal product contains 180 nanograms of benzyl alcohol in each tablet. Benzyl alcohol may cause allergic reactions. Intravenous administration of benzyl alcohol has been associated with serious adverse events and death in neonates (agonal breathing syndrome). The minimum amount of benzyl alcohol at which toxicity occurs is not known. Increased risk due to accumulation in young children. Large volumes should be used with caution and only if necessary, especially in subjects with hepatic or renal insufficiency due to the risk of accumulation and toxicity (metabolic acidosis). This medicinal product contains 210 nanograms of sulphur dioxide which may rarely cause severe hypersensitivity reactions and bronchospasm. This medicinal product contains 30 mg of aspartame in each effervescent tablet. Aspartame is a source of phenylalanine and may be harmful for people with phenylketonuria. This medicinal product contains glucose. Patients with rare glucose-galactose malabsorption problems should not take this medicine. It may also be harmful to the teeth. Calcium Sandoz effervescent tablets should be kept out of the reach of children. Information for diabetics : One effervescent tablet contains 0.002 units of carbohydrates and is therefore suitable for diabetics.

INTERACTIONS

Interactions Calcium Sandoz 500 mg 20 effervescent tablets - Which medicines or foods can modify the effect of Calcium Sandoz 500 mg 20 effervescent tablets?

Thiazide diuretics reduce urinary calcium excretion. Due to the increased risk of hypercalcemia, serum calcium should be regularly monitored during concomitant use of thiazide diuretics. Systemic corticosteroids reduce calcium absorption. During concomitant use, it may be necessary to increase the dose of Calcium Sandoz. Tetracycline preparations administered simultaneously with calcium preparations may not be well absorbed. For this reason, tetracycline-containing preparations should be administered at least 2 hours before or 4-6 hours after oral calcium intake. Hypercalcemia resulting from calcium treatment may increase the toxicity of cardiac glycosides. Patients should be monitored for electrocardiogram (ECG) and serum calcium levels. In case of concomitant oral treatment with bisphosphonates or sodium fluoride, this preparation should be administered at least 3 hours before Calcium Sandoz, since the gastrointestinal absorption of both bisphosphonates and sodium fluoride may be reduced. Oxalic acid (present in spinach and rhubarb) and phytic acid (present in whole grains) can inhibit calcium absorption by forming insoluble compounds with calcium ions. Patients should not take calcium-containing products within 2 hours of consuming foods rich in oxalic and phytic acid.

SIDE EFFECTS

Like all medicines, Calcium Sandoz 500 mg 20 effervescent tablets can cause side effects - What are the side effects of Calcium Sandoz 500 mg 20 effervescent tablets?

Adverse reactions are listed below, according to system organ class and frequency. Frequency is defined as: uncommon (>1/1,000, <1/100), rare (>1/10,000, <1/1,000) or very rare (<1/10,000), including isolated reports. Immune system disorders . Rare : hypersensitivity, such as rash, pruritus, urticaria. Very rare : isolated cases of systemic allergic reactions (anaphylactic reactions, facial oedema, angioneurotic oedema) have been reported. Metabolism and nutrition disorders . Uncommon : hypercalcaemia, hypercalciuria. Gastrointestinal disorders . Rare : flatulence, constipation, diarrhoea, nausea, vomiting, abdominal pain. Reporting of suspected adverse reactions Reporting suspected adverse reactions that occur after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions to the national reporting system at: https://www.aifa.gov.it/content/segnalazioni-reazioni-avverse.

OVERDOSE

Overdose Calcium Sandoz 500 mg 20 effervescent tablets - What are the risks of Calcium Sandoz 500 mg 20 effervescent tablets in case of overdose?

Overdose leads to hypercalciuria and hypercalcemia. Symptoms of hypercalcemia may include nausea, vomiting, thirst, polydipsia, polyuria, dehydration, and constipation. Chronic overdose resulting in hypercalcemia may cause vascular and organ calcification. The threshold for calcium intoxication is supplementation in excess of 2,000 mg per day, taken for many months. Treatment of overdose In case of intoxication, treatment should be stopped immediately and fluid deficiency should be corrected. In chronic overdose where hypercalcemia is present, the initial therapeutic phase consists of hydration with saline. A loop diuretic (e.g. furosemide) may then be used to further increase calcium excretion and prevent volume overload, but thiazide diuretics should be avoided. In patients with renal insufficiency, hydration is ineffective and they should undergo dialysis. In case of persistent hypercalcemia, contributing factors must be excluded, e.g. vitamin A or D, hypervitaminosis, primary hyperparathyroidism, malignancies, renal insufficiency or immobilization.

PREGNANCY AND BREASTFEEDING

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking Calcium Sandoz 500 mg 20 effervescent tablets.

The adequate daily intake (including food and supplements) for women with normal pregnancy and breastfeeding is 1,000-1,300 mg of calcium. During pregnancy, the daily calcium intake should not exceed 1,500 mg. Significant amounts of calcium are secreted into breast milk during breastfeeding but do not cause adverse effects on the newborn. In case of calcium deficiency, Calcium Sandoz effervescent tablets can be used during pregnancy and breastfeeding.

DRIVING AND USE OF MACHINERY

Taking Calcium Sandoz 500 mg 20 effervescent tablets before driving or using machines - Does Calcium Sandoz 500 mg 20 effervescent tablets affect driving or using machines?

Calcium Sandoz does not affect the ability to drive or use machines.