Aciclovir Sandoz 5% 3 g cream

Aciclovir Sandoz 5% 3g cream is a topical antiviral specifically formulated for the treatment of skin infections caused by Herpes simplex , such as cold sores and genital herpes , both in the primary and recurrent phases. Thanks to its high concentration of aciclovir , this 5% cream acts directly on the lesions, helping to reduce the duration and intensity of the typical symptoms of herpes, such as burning, itching and the formation of vesicles.

The cream formulation allows for rapid absorption and uniform distribution on the affected area, offering targeted relief and promoting faster healing of viral skin infections . Aciclovir Sandoz is indicated for those looking for an effective and practical herpes cream , ideal for both herpes on the lips and genital herpes. The 3g format is perfect for targeted use and to be carried with you at all times.

Thanks to its targeted action, Aciclovir Sandoz 5% cream represents a reliable solution for the topical treatment of Herpes simplex infections , helping to limit the spread of the virus and improve skin comfort. Choose this antiviral cream for rapid and effective support against the discomfort of herpes.

ACTIVE INGREDIENTS

Active ingredients contained in Aciclovir Sandoz 5 % 3 g cream - What is the active ingredient of Aciclovir Sandoz 5 % 3 g cream?

100 g of cream contains: Active ingredient: aciclovir 5.00 g.

EXCIPIENTS

Composition of Aciclovir Sandoz 5 % 3 g cream - What does Aciclovir Sandoz 5 % 3 g cream contain?

Purified water; propylene glycol; labrafil; vaseline oil; polaxamer 407; sodium lauryl sulfate; tefose.

DIRECTIONS

Therapeutic indications Aciclovir Sandoz 5 % 3 g cream - Why is Aciclovir Sandoz 5 % 3 g cream used? What is it used for?

The product in the cream formulation is indicated in the treatment of skin infections caused by Herpes simplex such as: primary or recurrent genital herpes and herpes labialis.

CONTRAINDICATIONS AND SIDE EFFECTS

Contraindications Aciclovir Sandoz 5 % 3 g cream - When should Aciclovir Sandoz 5 % 3 g cream not be used?

Known hypersensitivity to aciclovir, valaciclovir, propylene glycol, or other components of the formulation. Generally contraindicated in pregnancy and breastfeeding (see section 4.6).

DOSAGE

Quantity and method of taking Aciclovir Sandoz 5% 3g cream - How to take Aciclovir Sandoz 5% 3g cream?

The cream should be applied 5 times a day at approximately 4-hour intervals to the lesions or areas where they are developing as early as possible after the onset of the infection. It is particularly important to begin treatment of recurrent episodes during the prodrome phase or at the first appearance of the lesions. Treatment should continue for at least 5 days and up to a maximum of 10 if healing has not occurred.

CONSERVATION

Storage Aciclovir Sandoz 5% 3g cream - How is Aciclovir Sandoz 5% 3g cream stored?

Store at a temperature not exceeding 25°C.

WARNINGS

Warnings Aciclovir Sandoz 5 % 3 g cream - It is important to know that about Aciclovir Sandoz 5 % 3 g cream:

It is recommended that aciclovir cream should not be applied to mucous membranes (such as eyes, mouth or vagina) as it may be irritating. Particular care should be taken to avoid accidental introduction into the eye. Animal studies indicate that application of Aciclovir in the cream formulation to the vagina may cause reversible irritation. In severely immunocompromised patients (for example those with AIDS or who have received a bone marrow transplant) oral administration of aciclovir should be considered. Such patients should be encouraged to consult a doctor regarding the treatment of any infection. The excipient propylene glycol may cause skin irritation. Use of the product, especially if prolonged, may give rise to sensitization phenomena; if this occurs, treatment should be discontinued and the doctor consulted. Keep out of the reach and sight of children.

INTERACTIONS

Interactions Aciclovir Sandoz 5 % 3 g cream - Which medicines or foods can modify the effect of Aciclovir Sandoz 5 % 3 g cream?

Probenecid increases the mean half-life and the area under the plasma concentration curve of systemically administered Aciclovir. Clinical experience has not revealed interactions with other drugs.

SIDE EFFECTS

Like all medicines, Aciclovir Sandoz 5 % 3 g cream can cause side effects - What are the side effects of Aciclovir Sandoz 5 % 3 g cream?

The following convention has been used for the classification of undesirable effects in terms of frequency: very common ≥1/10; common ≥1/100 to <1/10; uncommon ≥1/1,000 to <1/100; rare ≥1/10,000 to <1/1,000; very rare <1/10,000. Data from clinical trials were used to assign frequency categories to the adverse reactions observed in clinical trials with aciclovir 3% ophthalmic ointment. Due to the nature of the adverse events observed, it was not possible to determine unequivocally which events were drug-related and which were disease-associated. Data from spontaneous reporting were used as a starting point for assigning frequencies to events observed in the post-marketing setting. Skin and subcutaneous tissue disorders Uncommon: transient stinging or burning sensation following application of aciclovir cream, mild drying or peeling of the skin, pruritus. Rare: erythema, contact dermatitis following application. Where sensitivity testing has been carried out, the reactive substances have been shown to be more often the components of the cream rather than aciclovir. Immune system disorders Very rare: immediate hypersensitivity reactions, including angioedema and urticaria.

OVERDOSE

Overdose Aciclovir Sandoz 5 % 3 g cream - What are the risks of Aciclovir Sandoz 5 % 3 g cream in case of overdose?

No adverse effects are expected even if the entire contents of a tube of aciclovir cream (500 mg) were taken orally, since single doses of 600 mg and daily doses of up to 3600 mg have been administered orally without any adverse effects. Single intravenous doses of up to 80 mg/kg have been administered accidentally without adverse effects. Aciclovir is dialysable.

PREGNANCY AND BREASTFEEDING

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking Aciclovir Sandoz 5% 3 g cream.

Pregnancy During this period the drug should be used only in cases of clear necessity and under the direct supervision of a physician. A post-marketing pregnancy registry for aciclovir has documented the effects on pregnancy in women exposed to any formulation of aciclovir. The results showed no increase in the number of birth defects among subjects exposed to aciclovir compared with the general population and any birth defects showed no unique features or recurrent patterns that would suggest a common cause. Systemic administration of aciclovir in internationally recognised standard tests did not produce embryotoxic or teratogenic effects in rabbits, rats or mice. In a non-standard test in rats, fetal abnormalities were observed, but only following the administration of subcutaneous doses high enough to cause maternal toxicity. The clinical relevance of these findings is uncertain. The use of aciclovir should be considered only if the potential benefits outweigh the possibility of unknown risks; Systemic exposure to aciclovir from topical application of aciclovir cream is, however, very limited. Breast-feeding Limited human data have shown that, following systemic administration, the drug passes into breast milk. However, the dosage received by a nursing infant following maternal use of aciclovir cream is insignificant. Caution is advised when using aciclovir during breast-feeding.

DRIVING AND USE OF MACHINERY

Taking Aciclovir Sandoz 5% 3g cream before driving or using machines - Does Aciclovir Sandoz 5% 3g cream affect driving or using machines?

There are no known negative effects of aciclovir on the ability to drive or use machines.