{"title":"Betadine","description":"\u003cp\u003eBetadine a base di iodopovidone, antisettico ad ampio spettro per la disinfezione della pelle e delle mucose. Disponibile in soluzione cutanea in più formati, flaconcini monodose, gel, garze impregnate pronte all’uso e soluzione vaginale. Per ferite, abrasioni, piccole ustioni e preparazione della cute. Spedizione veloce in 24\/48 ore.\u003c\/p\u003e","products":[{"product_id":"betadine-10-soluzione-cutanea-120ml","title":"Betadine 10% cutaneous solution 120ml","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDisinfection and cleaning of damaged skin (small superficial wounds, bedsores with limited involvement of the epidermis).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBetadine 10% cutaneous solution 100 ml contain: \u003cu\u003eActive ingredient:\u003c\/u\u003e Povidone iodine (10% iodine) g 10 For the complete list of excipients, see section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% cutaneous solution: \u003c\/u\u003eGlycerol, Macrogol lauryl ether, Dibasic sodium phosphate dihydrate, Citric acid monohydrate, Sodium hydroxide, Purified water.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHypersensitivity to the active substance or to any of the excipients listed in paragraph 6.1. Hyperthyroidism Do not use in children under six months of age.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% cutaneous solution:\u003c\/u\u003e It is applied 2 times a day directly on small wounds and skin infections. A quantity of 5 ml of solution (containing 50 mg of iodine) is sufficient to treat an area of ​​approximately 15 cm on each side. For skin antisepsis: apply a protective layer of the brown solution until a medium intensity color is obtained: a non-staining surface film is formed.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% cutaneous solution\u003c\/u\u003e: Store at a temperature not exceeding 25°C\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor external use only. This medicine must not be applied to severely damaged skin and large surfaces. Do not use for prolonged treatments: use, especially if prolonged, may give rise to sensitization phenomena. In this case, treatment should be discontinued and a clinical evaluation performed. Particular caution should be used in patients with pre-existing renal insufficiency who require regular applications of Betadine on damaged skin (see section 5.2). Patients with goiter, thyroid nodules, or other acute and non-acute thyroid conditions are at risk of developing thyroid hyperfunction (hyperthyroidism) following administration of large amounts of iodine. In this patient population, povidone iodine solution should not be used for a prolonged period of time and on large body surfaces. Even after the end of treatment, it is necessary to look for early symptoms of possible hyperthyroidism and monitor thyroid function. Do not use at least 10 days before performing a scan or after a radioactive iodine scan or in the treatment of thyroid cancer with radioactive iodine. The pediatric population is at greater risk of developing hypothyroidism following applications of high doses of iodine. Due to the permeability of the skin and their high sensitivity to iodine, the use of povidone iodine should be reduced to the bare minimum in children. A check of the child's thyroid function (for example T4 and TSH levels) may be necessary. Any oral ingestion of povidone iodine by the child should be avoided. In pediatric age use only under strict supervision and in cases of actual need. Accidental ingestion or inhalation of some disinfectants can have serious, sometimes fatal consequences. Avoid contact with eyes.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAvoid the simultaneous use of other antiseptics and detergents. The polyvinylpyrrolidone-iodine complex is effective at pH values ​​between 2.0 and 7.0. It is possible that the complex reacts with proteins or other unsaturated organic compounds, and this leads to a reduction in its effectiveness. The concomitant use of preparations with enzymatic components for the treatment of wounds leads to a weakening of the effects of both substances. Povidone iodine should not be used simultaneously with products containing mercury salts or benzoin compounds, carbonates, tannic acid, alkali, hydrogen peroxide, taurolidine and silver. The use of povidone iodine-containing products concomitantly with other octedin-containing antiseptics in the same or adjacent sites may cause temporary dark discoloration of the affected areas. The oxidative effect of povidone iodine preparations can cause false positive results of some laboratory diagnostic tests (for example tests with toluidine or guaiac gum for the determination of hemoglobin or glucose in feces or urine). Avoid habitual use in patients receiving concomitant treatment with lithium. Absorption of iodine from povidone iodine solution may reduce thyroid iodine uptake. This may interfere with various tests (thyroid scan, determination of iodine-binding proteins, radioactive iodine diagnostics) and may make planned treatment of the thyroid with iodine (radioactive iodine therapy) impossible. After the end of treatment, an adequate period of time must pass before performing a new scan.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eUndesirable effects are classified according to their frequency: Very common (≥ 1\/10) Common (\u003e 1\/100 to \u003c 1\/10) Uncommon (≥ 1\/1,000 to \u003c 1\/100) Rare (≥ 1\/10,000 to \u003c 1\/1,000) Very rare (\u003c 1\/10,000) Not known (frequency cannot be estimated from the data available) \u003cu\u003eImmune system disorders\u003c\/u\u003e Rare: Hypersensitivity Very rare: Anaphylactic reaction \u003cu\u003eEndocrine disorders\u003c\/u\u003e Very rare: Hyperthyroidism* (sometimes with symptoms such as tachycardia or agitation) Not known: Hypothyroidism *** \u003cu\u003eMetabolism and nutrition disorders\u003c\/u\u003e Not known: Electrolyte imbalance **, Metabolic acidosis ** \u003cu\u003ePathologies of the skin and subcutaneous tissue\u003c\/u\u003e Rare: Contact dermatitis (with symptoms such as erythema, microvesicles and pruritus) Very rare: Angioedema Not known: Exfoliative dermatitis \u003cu\u003eRenal and urinary disorders\u003c\/u\u003e Not known: Acute renal failure **, Abnormal blood osmolarity ** *In patients with a history of thyroid disease (see section Warnings and special precautions for use) as a result of high iodine uptake, for example after long-term use of povidone iodine solution to treat wounds and burns on large skin areas. **May occur following the uptake of high quantities of povidone iodine (for example in the treatment of burns) ***Hypothyroidism following prolonged or extensive use of povidone iodine Reporting of suspected adverse reactions Reporting of suspected adverse reactions that occur after authorization of the medicinal product is important, as it allows continuous monitoring of the benefit\/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at: http:\/\/www.agenziafarmaco.gov.it\/content\/come-segnalare-una-sosp etta-reazione-avversa.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn case of overdose, whether intentional or accidental, hypothyroidism or hyperthyroidism may occur. Systemic absorption of iodine after repeated applications of the product on large wounds or severe burns may produce a number of symptoms such as: metallic taste, increased salivation, burning or stinging in the mouth and throat, irritation or swelling of the eyes, fever, skin rash, diarrhea and gastrointestinal disorders, hypotension, tachycardia, metabolic acidosis, hypernatremia, failure of renal function, pulmonary edema and shock. In case of accidental ingestion of large quantities of product, institute symptomatic and supportive treatment with particular attention to electrolyte balance and renal and thyroid function.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDuring pregnancy and breastfeeding, povidone iodine solution should be used only if strictly necessary and at the lowest possible dose, due to the ability of iodine to cross the placenta and be secreted into breast milk and the high sensitivity of the fetus and newborn to iodine. Furthermore, iodine is more concentrated in breast milk than in serum, therefore it can cause transient hypothyroidism with an increase in TSH (thyroid stimulating hormone) in the fetus or newborn\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBetadine does not affect the ability to drive or use machines.\u003c\/p\u003e","brand":"Viatris Healthcare","offers":[{"title":"Default Title","offer_id":51131184283975,"sku":"023907292","price":9.21,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/viatris-healthcare-limited-betadine-10-soluzione-cutanea-120ml-farmacia-dottor-tili-1213792408.jpg?v=1767132527"},{"product_id":"betadine-10-soluzione-cutanea-50ml","title":"Betadine 10% cutaneous solution 50ml","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDisinfection and cleaning of damaged skin (small superficial wounds, bedsores with limited involvement of the epidermis).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBetadine 10% cutaneous solution 100 ml contain: \u003cu\u003eActive ingredient:\u003c\/u\u003e Povidone iodine (10% iodine) g 10 For the complete list of excipients, see section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% cutaneous solution: \u003c\/u\u003eGlycerol, Macrogol lauryl ether, Dibasic sodium phosphate dihydrate, Citric acid monohydrate, Sodium hydroxide, Purified water.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHypersensitivity to the active substance or to any of the excipients listed in paragraph 6.1. Hyperthyroidism Do not use in children under six months of age.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% cutaneous solution:\u003c\/u\u003e It is applied 2 times a day directly on small wounds and skin infections. A quantity of 5 ml of solution (containing 50 mg of iodine) is sufficient to treat an area of ​​approximately 15 cm on each side. For skin antisepsis: apply a protective layer of the brown solution until a medium intensity color is obtained: a non-staining surface film is formed.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% cutaneous solution\u003c\/u\u003e: Store at a temperature not exceeding 25°C\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor external use only. This medicine must not be applied to severely damaged skin and large surfaces. Do not use for prolonged treatments: use, especially if prolonged, may give rise to sensitization phenomena. In this case, treatment should be discontinued and a clinical evaluation performed. Particular caution should be used in patients with pre-existing renal insufficiency who require regular applications of Betadine on damaged skin (see section 5.2). Patients with goiter, thyroid nodules, or other acute and non-acute thyroid conditions are at risk of developing thyroid hyperfunction (hyperthyroidism) following administration of large amounts of iodine. In this patient population, povidone iodine solution should not be used for a prolonged period of time and on large body surfaces. Even after the end of treatment, it is necessary to look for early symptoms of possible hyperthyroidism and monitor thyroid function. Do not use at least 10 days before performing a scan or after a radioactive iodine scan or in the treatment of thyroid cancer with radioactive iodine. The pediatric population is at greater risk of developing hypothyroidism following applications of high doses of iodine. Due to the permeability of the skin and their high sensitivity to iodine, the use of povidone iodine should be reduced to the bare minimum in children. A check of the child's thyroid function (for example T4 and TSH levels) may be necessary. Any oral ingestion of povidone iodine by the child should be avoided. In pediatric age use only under strict supervision and in cases of actual need. Accidental ingestion or inhalation of some disinfectants can have serious, sometimes fatal consequences. Avoid contact with eyes.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAvoid the simultaneous use of other antiseptics and detergents. The polyvinylpyrrolidone-iodine complex is effective at pH values ​​between 2.0 and 7.0. It is possible that the complex reacts with proteins or other unsaturated organic compounds, and this leads to a reduction in its effectiveness. The concomitant use of preparations with enzymatic components for the treatment of wounds leads to a weakening of the effects of both substances. Povidone iodine should not be used simultaneously with products containing mercury salts or benzoin compounds, carbonates, tannic acid, alkali, hydrogen peroxide, taurolidine and silver. The use of povidone iodine-containing products concomitantly with other octedin-containing antiseptics in the same or adjacent sites may cause temporary dark discoloration of the affected areas. The oxidative effect of povidone iodine preparations can cause false positive results of some laboratory diagnostic tests (for example tests with toluidine or guaiac gum for the determination of hemoglobin or glucose in feces or urine). Avoid habitual use in patients receiving concomitant treatment with lithium. Absorption of iodine from povidone iodine solution may reduce thyroid iodine uptake. This may interfere with various tests (thyroid scan, determination of iodine-binding proteins, radioactive iodine diagnostics) and may make planned treatment of the thyroid with iodine (radioactive iodine therapy) impossible. After the end of treatment, an adequate period of time must pass before performing a new scan.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eUndesirable effects are classified according to their frequency: Very common (≥ 1\/10) Common (\u003e 1\/100 to \u003c 1\/10) Uncommon (≥ 1\/1,000 to \u003c 1\/100) Rare (≥ 1\/10,000 to \u003c 1\/1,000) Very rare (\u003c 1\/10,000) Not known (frequency cannot be estimated from the data available) \u003cu\u003eImmune system disorders\u003c\/u\u003e Rare: Hypersensitivity Very rare: Anaphylactic reaction \u003cu\u003eEndocrine disorders\u003c\/u\u003e Very rare: Hyperthyroidism* (sometimes with symptoms such as tachycardia or agitation) Not known: Hypothyroidism *** \u003cu\u003eMetabolism and nutrition disorders\u003c\/u\u003e Not known: Electrolyte imbalance **, Metabolic acidosis ** \u003cu\u003ePathologies of the skin and subcutaneous tissue\u003c\/u\u003e Rare: Contact dermatitis (with symptoms such as erythema, microvesicles and pruritus) Very rare: Angioedema Not known: Exfoliative dermatitis \u003cu\u003eRenal and urinary disorders\u003c\/u\u003e Not known: Acute renal failure **, Abnormal blood osmolarity ** *In patients with a history of thyroid disease (see section Warnings and special precautions for use) as a result of high iodine uptake, for example after long-term use of povidone iodine solution to treat wounds and burns on large skin areas. **May occur following the uptake of high quantities of povidone iodine (for example in the treatment of burns) ***Hypothyroidism following prolonged or extensive use of povidone iodine Reporting of suspected adverse reactions Reporting of suspected adverse reactions that occur after authorization of the medicinal product is important, as it allows continuous monitoring of the benefit\/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at: http:\/\/www.agenziafarmaco.gov.it\/content\/come-segnalare-una-sosp etta-reazione-avversa.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn case of overdose, whether intentional or accidental, hypothyroidism or hyperthyroidism may occur. Systemic absorption of iodine after repeated applications of the product on large wounds or severe burns may produce a number of symptoms such as: metallic taste, increased salivation, burning or stinging in the mouth and throat, irritation or swelling of the eyes, fever, skin rash, diarrhea and gastrointestinal disorders, hypotension, tachycardia, metabolic acidosis, hypernatremia, failure of renal function, pulmonary edema and shock. In case of accidental ingestion of large quantities of product, institute symptomatic and supportive treatment with particular attention to electrolyte balance and renal and thyroid function.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDuring pregnancy and breastfeeding, povidone iodine solution should be used only if strictly necessary and at the lowest possible dose, due to the ability of iodine to cross the placenta and be secreted into breast milk and the high sensitivity of the fetus and newborn to iodine. Furthermore, iodine is more concentrated in breast milk than in serum, therefore it can cause transient hypothyroidism with an increase in TSH (thyroid stimulating hormone) in the fetus or newborn\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBetadine does not affect the ability to drive or use machines.\u003c\/p\u003e","brand":"Viatris Healthcare","offers":[{"title":"Default Title","offer_id":51131201978695,"sku":"023907177","price":6.6,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/viatris-healthcare-limited-betadine-10-soluzione-cutanea-50ml-farmacia-dottor-tili-1213792387.jpg?v=1767132818"},{"product_id":"betadine-10-garze-impregnate-10","title":"Betadine 10 gauzes impregnated 10%","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% Cutaneous solution, alcoholic:\u003c\/u\u003e Disinfection and cleaning of damaged skin (small superficial wounds, bedsores with limited involvement of the epidermis). The medicine can be used to disinfect the skin before surgery. \u003cu\u003eBetadine 1% Mouthwash:\u003c\/u\u003e Disinfection of the oral mucosa. \u003cu\u003eBetadine 10% Gel:\u003c\/u\u003e Disinfection of damaged skin (small superficial wounds, bedsores with involvement limited to the epidermis). \u003cu\u003eBetadine 10% Impregnated gauzes:\u003c\/u\u003e Disinfection of damaged skin (small superficial wounds, bedsores with involvement limited to the epidermis).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% Cutaneous solution, alcoholic:\u003c\/u\u003e 100 ml contain: Active ingredient: Povidone iodine (10% iodine) 10 g. \u003cu\u003eBetadine 1% Mouthwash\u003c\/u\u003e: 100 ml contain: Active ingredient: Povidone iodine (10% iodine) 1.0 g. Excipient with known effects: ethanol \u003cu\u003eBetadine 10% Gel:\u003c\/u\u003e 100 g of gel or gel contains: Active ingredient: Povidone iodine (10% iodine) 10 g. \u003cu\u003eBetadine 10% Impregnated gauzes\u003c\/u\u003e 1 1 dm² gauze tablet of 3 g contains: Active ingredient: Povidone iodine (10% iodine) 0.25 g. For the full list of excipients, see section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% Cutaneous solution, alcoholic:\u003c\/u\u003e Isopropyl alcohol, Citric acid, Dibasic sodium phosphate, Purified water. \u003cu\u003eBetadine 10% Gel:\u003c\/u\u003e Polyethylene glycol 400, Polyethylene glycol 4000, Polyethylene glycol 6000, Purified water. \u003cu\u003eBetadine 1% Mouthwash:\u003c\/u\u003e Ethanol, Glycerol, Eucalyptol, Menthol, Sodium saccharin, Citric acid monohydrate, Dibasic sodium phosphate dihydrate, Potassium iodate Purified water. \u003cu\u003eBetadine 10% Impregnated gauzes:\u003c\/u\u003e Polyethylene glycol 400, Polyethylene glycol 4000, Polyethylene glycol 6000, Purified water.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e• Hypersensitivity to the active substance or to any of the excipients listed in paragraph 6.1. • Hyperthyroidism • Do not use in children under 6 months of age. • Mouthwash should not be used in children under 6 years of age.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% Cutaneous solution, alcoholic:\u003c\/u\u003e Apply undiluted Betadine alcohol solution once or twice to the entire skin area to be disinfected. Distribute the product with sterile gauze. Leave to dry completely. \u003cu\u003eBetadine 1% Mouthwash:\u003c\/u\u003e Dilute to your taste, only when necessary, keeping in mind that the effectiveness is maintained at the dilution of 1 part Betadine to 2 parts water, and gargle 2-3 times a day. DO NOT EXCEED THE RECOMMENDED DOSES. \u003cu\u003eBetadine 10% Gel:\u003c\/u\u003e Apply a light layer of gel 2 times a day as needed directly to the affected (small) area. DO NOT EXCEED THE RECOMMENDED DOSES. \u003cu\u003eBetadine 10% Impregnated gauzes:\u003c\/u\u003e Apply 1 gauze, 1-3 times a day. DO NOT EXCEED THE RECOMMENDED DOSES.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 1% Mouthwash\u003c\/u\u003e: Store at a temperature not exceeding 25°C. \u003cu\u003eBetadine 10% Cutaneous solution, alcoholic\u003c\/u\u003e: Store at a temperature not exceeding 25°C \u003cu\u003eBetadine 10% Gel and Betadine 10% Impregnated gauzes\u003c\/u\u003e: Store at a temperature not exceeding 30°C\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor external use only. The product must not be applied to severely damaged skin and large surfaces. Do not use for prolonged treatments: use, especially if prolonged, may give rise to sensitization phenomena. In this case, treatment should be discontinued and a clinical evaluation performed. Particular caution should be used in patients with pre-existing renal insufficiency who require regular applications of Betadine on damaged skin (see section 5.2). Patients with goiter, thyroid nodules, or other acute and non-acute thyroid conditions are at risk of developing thyroid hyperfunction (hyperthyroidism) following administration of large amounts of iodine. In this patient population, povidone iodine solution should not be used for a prolonged period of time and on large body surfaces. Even after the end of treatment, it is necessary to look for early symptoms of possible hyperthyroidism and monitor thyroid function. Do not use at least 10 days before performing a scan or after a radioactive iodine scan or in the treatment of thyroid cancer with radioactive iodine. The pediatric population is at greater risk of developing hypothyroidism following applications of high doses of iodine. Due to the permeability of the skin and their high sensitivity to iodine, the use of povidone iodine should be reduced to the bare minimum in children. A check of the child's thyroid function (for example, T4 and TSH levels) may be necessary. Any oral ingestion of povidone iodine by the child should be avoided. In pediatric age use only under strict supervision and in cases of actual need. Accidental ingestion or inhalation of some disinfectants can have serious, sometimes fatal, consequences. Avoid contact with eyes. \u003cu\u003eBetadine 10% cutaneous solution, alcoholic:\u003c\/u\u003e The alcohol solution is highly flammable: it must dry completely before any device (especially high-frequency surgical devices) is applied. In pre-operative preparation, avoid accumulation under the patient, as chemical burns to the skin may occur. Prolonged exposure to solution-related moist conditions may cause irritation or, rarely, severe skin reactions. If skin irritation, contact dermatitis or hypersensitivity occurs, discontinue use. Do not heat before application. \u003cu\u003eBetadine 1% mouthwash:\u003c\/u\u003e Care should be taken in case of oropharyngeal use to avoid inhalation of Betadine 1% mouthwash through the respiratory tract as it may cause complications such as pneumonia. This may particularly occur in intubated patients. Long-term use of povidone iodine for gargling should be avoided in pregnant women, breastfeeding mothers and people with a high risk of developing thyroid dysfunction due to excessive iodine intake (see sections 4.6 and 5.2). \u003ci\u003eImportant information about some excipients\u003c\/i\u003e Betadine 1% Mouthwash contains less than 1 mmol (23 mg) sodium per 20 ml of mouthwash, i.e. essentially 'sodium-free'. Betadine 1% Mouthwash contains 681.88 mg of alcohol (ethanol) in 20 ml of mouthwash. The amount in 20ml of this medicine is equivalent to less than 18ml of beer or 8ml of wine. The small amount of alcohol in this medicine will not produce any relevant effects.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAvoid the simultaneous use of other antiseptics and detergents. The polyvinylpyrrolidone-iodine complex is effective and stable at pH values ​​between 2.0 and 7.0. It is possible that the complex reacts with proteins or other unsaturated organic compounds, and this leads to a reduction in its effectiveness. The concomitant use of preparations with enzymatic components for the treatment of wounds leads to a weakening of the effects of both substances. Povidone iodine should not be used simultaneously with products containing mercury salts or benzonium compounds, carbonates, tannic acid, alkali, hydrogen peroxide, taurolidine and silver. The use of povidone iodine-containing products concomitantly with other octedin-containing antiseptics in the same or adjacent sites may cause temporary dark discoloration of the affected areas. The oxidative effect of povidone iodine preparations can cause false positive results of some laboratory diagnostic tests (for example tests with toluidine or guaiac gum for the determination of hemoglobin or glucose in feces or urine). Avoid routine use in patients receiving concomitant treatment with lithium. Absorption of iodine from povidone iodine solution may reduce thyroid iodine uptake. This may interfere with various tests (thyroid scan, determination of iodine-binding proteins, radioactive iodine diagnostics) and may make planned treatment of the thyroid with iodine (radioactive iodine therapy) impossible. After the end of treatment, an adequate period of time must pass before performing a new scan.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eUndesirable effects are classified according to their frequency: Very common (≥ 1\/10) Common (\u003e 1\/100 to \u003c 1\/10) Uncommon (≥ 1\/1,000 to \u003c 1\/100) Rare (≥ 1\/10,000 to \u003c 1\/1,000) Very rare (\u003c 1\/10,000) Not known (frequency cannot be estimated from the data available) \u003cu\u003eImmune system disorders \u003c\/u\u003e Rare Hypersensitivity Very rare Anaphylactic reaction \u003cu\u003eEndocrine disorders\u003c\/u\u003e Very rare Hyperthyroidism * (sometimes with symptoms such as tachycardia or agitation) Not known Hypothyroidism *** \u003cu\u003eMetabolism and nutrition disorders\u003c\/u\u003e Not known Electrolyte imbalance **, Metabolic acidosis ** \u003cu\u003eRespiratory, thoracic and mediastinal disorders \u003c\/u\u003e Not known Pneumonia ***** (only when using Betadine 1% mouthwash) \u003cu\u003ePathologies of the skin and subcutaneous tissue \u003c\/u\u003e Rare Contact dermatitis (with symptoms such as erythema, microvesicles and itching) Very rare Angioedema Not known Exfoliative dermatitis, Dry skin ^^ (only in case of use of Betadine 10% cutaneous solution, alcoholic) \u003cu\u003eRenal and urinary disorders\u003c\/u\u003e Not known Acute renal failure **, Abnormal blood osmolarity ** \u003cu\u003eInjury, poisoning and procedural complications\u003c\/u\u003e Not known Chemical skin burn ****, Thermal burn ^ (only in case of use of Betadine 10% cutaneous solution, alcoholic) *In patients with a history of thyroid pathologies (see paragraph Warnings and special precautions for use) following high iodine uptake, for example after long-term use of povidone-iodine solution for the treatment of wounds and burns on large skin areas. **May occur as a result of uptake of high quantities of povidone iodine (e.g. in the treatment of burns) ***Hypothyroidism following prolonged or extensive use of povidone iodine **** As a result of “accumulation” behind the patient during pre-operative preparation *****Complications due to inhalation - see section 4.4 ^Due to the high flammability, the alcoholic povidone iodine solution must dry completely before devices (particularly high-pressure surgical devices) can be used high frequency) ^^May occur after repeated applications due to the high alcohol content in the solution; the risk is greater for the genital area (for example for the scrotum) \u003cu\u003eReporting of suspected adverse reactions \u003c\/u\u003e Reporting suspected adverse reactions that occur after authorization of the medicinal product is important, as it allows continuous monitoring of the benefit\/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at: www.aifa.gov.it\/content\/segnalazioni-reazioni-avverse\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn case of overdose, whether intentional or accidental (highly unlikely for pharmaceutical forms such as gauze), hypothyroidism or hyperthyroidism may occur. Systemic absorption of iodine after repeated applications of the product on large wounds or severe burns can produce a series of symptoms such as: metallic taste, increased salivation, burning or stinging in the mouth and throat, irritation or swelling of the eyes, fever, skin rash, diarrhea and gastrointestinal disorders, hypotension, tachycardia, metabolic acidosis, hypernatremia, failure of renal function, pulmonary edema and shock. In case of accidental ingestion of large quantities of the product, institute a symptomatic and supportive treatment with particular attention to electrolyte balance and renal and thyroid function.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDuring pregnancy and breastfeeding, povidone iodine solution should be used only if strictly necessary and at the lowest possible dose, due to the ability of iodine to cross the placenta and be secreted into breast milk and the high sensitivity of the fetus and newborn to iodine. Furthermore, iodine is more concentrated in breast milk than in serum, therefore it can cause transient hypothyroidism with an increase in TSH (thyroid stimulating hormone) in the fetus or newborn.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBetadine does not affect the ability to drive or use machines.\u003c\/p\u003e","brand":"Viatris Healthcare","offers":[{"title":"Default Title","offer_id":51131271217479,"sku":"023907140","price":11.02,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/viatris-healthcare-limited-betadine-10-garze-impregnate-10-farmacia-dottor-tili-1213792272.jpg?v=1767133151"},{"product_id":"betadine-10-soluzione-cutanea-500ml","title":"Betadine 10% cutaneous solution 500ml","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDisinfection and cleaning of damaged skin (small superficial wounds, bedsores with limited involvement of the epidermis).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBetadine 10% cutaneous solution 100 ml contain: \u003cu\u003eActive ingredient:\u003c\/u\u003e Povidone iodine (10% iodine) g 10 For the complete list of excipients, see section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% cutaneous solution: \u003c\/u\u003eGlycerol, Macrogol lauryl ether, Dibasic sodium phosphate dihydrate, Citric acid monohydrate, Sodium hydroxide, Purified water.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHypersensitivity to the active substance or to any of the excipients listed in paragraph 6.1. Hyperthyroidism Do not use in children under six months of age.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% cutaneous solution:\u003c\/u\u003e It is applied 2 times a day directly on small wounds and skin infections. A quantity of 5 ml of solution (containing 50 mg of iodine) is sufficient to treat an area of ​​approximately 15 cm on each side. For skin antisepsis: apply a protective layer of the brown solution until a medium intensity color is obtained: a non-staining surface film is formed.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% cutaneous solution\u003c\/u\u003e: Store at a temperature not exceeding 25°C\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor external use only. This medicine must not be applied to severely damaged skin and large surfaces. Do not use for prolonged treatments: use, especially if prolonged, may give rise to sensitization phenomena. In this case, treatment should be discontinued and a clinical evaluation performed. Particular caution should be used in patients with pre-existing renal insufficiency who require regular applications of Betadine on damaged skin (see section 5.2). Patients with goiter, thyroid nodules, or other acute and non-acute thyroid conditions are at risk of developing thyroid hyperfunction (hyperthyroidism) following administration of large amounts of iodine. In this patient population, povidone iodine solution should not be used for a prolonged period of time and on large body surfaces. Even after the end of treatment, it is necessary to look for early symptoms of possible hyperthyroidism and monitor thyroid function. Do not use at least 10 days before performing a scan or after a radioactive iodine scan or in the treatment of thyroid cancer with radioactive iodine. The pediatric population is at greater risk of developing hypothyroidism following applications of high doses of iodine. Due to the permeability of the skin and their high sensitivity to iodine, the use of povidone iodine should be reduced to the bare minimum in children. A check of the child's thyroid function (for example T4 and TSH levels) may be necessary. Any oral ingestion of povidone iodine by the child should be avoided. In pediatric age use only under strict supervision and in cases of actual need. Accidental ingestion or inhalation of some disinfectants can have serious, sometimes fatal consequences. Avoid contact with eyes.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAvoid the simultaneous use of other antiseptics and detergents. The polyvinylpyrrolidone-iodine complex is effective at pH values ​​between 2.0 and 7.0. It is possible that the complex reacts with proteins or other unsaturated organic compounds, and this leads to a reduction in its effectiveness. The concomitant use of preparations with enzymatic components for the treatment of wounds leads to a weakening of the effects of both substances. Povidone iodine should not be used simultaneously with products containing mercury salts or benzoin compounds, carbonates, tannic acid, alkali, hydrogen peroxide, taurolidine and silver. The use of povidone iodine-containing products concomitantly with other octedin-containing antiseptics in the same or adjacent sites may cause temporary dark discoloration of the affected areas. The oxidative effect of povidone iodine preparations can cause false positive results of some laboratory diagnostic tests (for example tests with toluidine or guaiac gum for the determination of hemoglobin or glucose in feces or urine). Avoid habitual use in patients receiving concomitant treatment with lithium. Absorption of iodine from povidone iodine solution may reduce thyroid iodine uptake. This may interfere with various tests (thyroid scan, determination of iodine-binding proteins, radioactive iodine diagnostics) and may make planned treatment of the thyroid with iodine (radioactive iodine therapy) impossible. After the end of treatment, an adequate period of time must pass before performing a new scan.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eUndesirable effects are classified according to their frequency: Very common (≥ 1\/10) Common (\u003e 1\/100 to \u003c 1\/10) Uncommon (≥ 1\/1,000 to \u003c 1\/100) Rare (≥ 1\/10,000 to \u003c 1\/1,000) Very rare (\u003c 1\/10,000) Not known (frequency cannot be estimated from the data available) \u003cu\u003eImmune system disorders\u003c\/u\u003e Rare: Hypersensitivity Very rare: Anaphylactic reaction \u003cu\u003eEndocrine disorders\u003c\/u\u003e Very rare: Hyperthyroidism* (sometimes with symptoms such as tachycardia or agitation) Not known: Hypothyroidism *** \u003cu\u003eMetabolism and nutrition disorders\u003c\/u\u003e Not known: Electrolyte imbalance **, Metabolic acidosis ** \u003cu\u003ePathologies of the skin and subcutaneous tissue\u003c\/u\u003e Rare: Contact dermatitis (with symptoms such as erythema, microvesicles and pruritus) Very rare: Angioedema Not known: Exfoliative dermatitis \u003cu\u003eRenal and urinary disorders\u003c\/u\u003e Not known: Acute renal failure **, Abnormal blood osmolarity ** *In patients with a history of thyroid disease (see section Warnings and special precautions for use) as a result of high iodine uptake, for example after long-term use of povidone iodine solution to treat wounds and burns on large skin areas. **May occur following the uptake of high quantities of povidone iodine (for example in the treatment of burns) ***Hypothyroidism following prolonged or extensive use of povidone iodine Reporting of suspected adverse reactions Reporting of suspected adverse reactions that occur after authorization of the medicinal product is important, as it allows continuous monitoring of the benefit\/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at: http:\/\/www.agenziafarmaco.gov.it\/content\/come-segnalare-una-sosp etta-reazione-avversa.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn case of overdose, whether intentional or accidental, hypothyroidism or hyperthyroidism may occur. Systemic absorption of iodine after repeated applications of the product on large wounds or severe burns may produce a number of symptoms such as: metallic taste, increased salivation, burning or stinging in the mouth and throat, irritation or swelling of the eyes, fever, skin rash, diarrhea and gastrointestinal disorders, hypotension, tachycardia, metabolic acidosis, hypernatremia, failure of renal function, pulmonary edema and shock. In case of accidental ingestion of large quantities of product, institute symptomatic and supportive treatment with particular attention to electrolyte balance and renal and thyroid function.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDuring pregnancy and breastfeeding, povidone iodine solution should be used only if strictly necessary and at the lowest possible dose, due to the ability of iodine to cross the placenta and be secreted into breast milk and the high sensitivity of the fetus and newborn to iodine. Furthermore, iodine is more concentrated in breast milk than in serum, therefore it can cause transient hypothyroidism with an increase in TSH (thyroid stimulating hormone) in the fetus or newborn\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBetadine does not affect the ability to drive or use machines.\u003c\/p\u003e","brand":"Viatris Healthcare","offers":[{"title":"Default Title","offer_id":51131368472903,"sku":"023907280","price":13.3,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/viatris-healthcare-limited-betadine-10-soluzione-cutanea-500ml-farmacia-dottor-tili-1213791891.png?v=1767150290"},{"product_id":"betadine-10-concentrato-5-flaconi-140ml-5-fialoidi-10ml-5-canule-soluzione-vaginale","title":"Betadine 10% concentrate 5 bottles 140ml + 5 vials 10ml + 5 cannulas Vaginal solution","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDisinfectant of the vaginal mucosa.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eComposition of the vial - 100 ml contains: \u003cu\u003eActive ingredient: \u003c\/u\u003ePovidone iodine 10 g For the complete list of excipients, see section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn the vial: Purified water. In the bottle: dodecylglucoside, Intimate hygiene perfume A 402580, Purified water.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e• Hypersensitivity to the active substance, to any of the excipients listed in paragraph 6.1. • Hyperthyroidism\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAfter pouring the contents of the vial into the bottle, insert the vaginal cannula and perform irrigation 1-2 times a day. After a reasonable period of time without appreciable results, consult your doctor.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eStore away from heat.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDo not use for prolonged treatments. Particular caution should be used in patients with pre-existing renal insufficiency who require regular applications of Betadine on damaged skin. Use of the product, especially if prolonged, can give rise to sensitization phenomena. In this case, stop treatment and adopt suitable therapeutic measures. Patients with goiter, thyroid nodules, or other acute and non-acute thyroid conditions are at risk of developing thyroid hyperfunction (hyperthyroidism) following administration of large amounts of iodine. In this patient population, povidone iodine solution should not be used for a prolonged period of time and on large body surfaces unless strictly indicated. Even after the end of treatment, early symptoms of possible hyperthyroidism should be looked for and, if necessary, thyroid function should be monitored. Do not use at least 10 days before performing scintigraphy or after scintigraphy with radioactive iodine or in the treatment of thyroid cancer with radioactive iodine. The pediatric population is at greater risk of developing hypothyroidism following the administration of high doses of iodine. Due to the permeability of the skin and their high sensitivity to iodine, the use of povidone iodine should be reduced to the bare minimum in children. A check of the child's thyroid function (for example T4 and TSH levels) may be necessary. Any oral ingestion of povidone iodine by the child should be avoided. In pediatric age use only under strict supervision and in cases of actual need. Accidental ingestion or inhalation of some disinfectants can have serious, sometimes fatal, consequences. Avoid contact with eyes.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAvoid the simultaneous use of other antiseptics and detergents. The polyvinylpyrrolidone-iodine complex is effective at pH values ​​between 2.0 and 7.0. It is possible that the complex reacts with proteins or other unsaturated organic compounds, and this leads to a reduction in its effectiveness. The concomitant use of preparations with enzymatic components for the treatment of wounds leads to a weakening of the effects of both substances. Povidone iodine should not be used simultaneously with products containing mercury salts or benzoin compounds, carbonates, tannic acid, alkali, hydrogen peroxide, taurolidine and silver. The use of povidone iodine-containing products concomitantly with other octedin-containing antiseptics in the same or adjacent sites may cause temporary dark discoloration of the affected areas. The oxidative effect of povidone iodine preparations can cause false positive results of some laboratory diagnostic tests (for example tests with toluidine or guaiac gum for the determination of hemoglobin or glucose in feces or urine). Avoid habitual use in patients receiving concomitant treatment with lithium. Absorption of iodine from povidone iodine solution may reduce thyroid iodine uptake. This may interfere with various tests (thyroid scan, determination of iodine-binding proteins, radioactive iodine diagnostics) and may make planned treatment of the thyroid with iodine (radioactive iodine therapy) impossible. After the end of treatment, an adequate period of time must pass before performing a new scan.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eUndesirable effects are classified according to their frequency: Very common (≥ 1\/10) Common (\u003e 1\/100 to \u003c 1\/10) Uncommon (≥ 1\/1,000 to \u003c 1\/100) Rare (≥ 1\/10,000 to \u003c 1\/1,000) Very rare (\u003c 1\/10,000) Not known (frequency cannot be estimated from the data available) \u003cu\u003eImmune system disorders\u003c\/u\u003e Rare: Hypersensitivity Very rare: Anaphylactic reaction \u003cu\u003eEndocrine disorders\u003c\/u\u003e Very rare: Hyperthyroidism * (sometimes with symptoms such as tachycardia or agitation) Not known: Hypothyroidism *** \u003cu\u003eMetabolism and nutrition disorders\u003c\/u\u003e Not known: Electrolyte imbalance **, Metabolic acidosis ** \u003cu\u003ePathologies of the skin and subcutaneous tissue\u003c\/u\u003e Rare: Contact dermatitis (with symptoms such as erythema, microvesicles and pruritus) Very rare: Angioedema \u003cu\u003eRenal and urinary disorders\u003c\/u\u003e Not known: Acute renal failure **, Abnormal blood osmolarity ** *In patients with a history of thyroid disease (see section Warnings and special precautions for use) as a result of high iodine uptake, for example after long-term use of povidone iodine solution to treat wounds and burns on large skin areas. **May occur following uptake of high amounts of povidone iodine (e.g. in the treatment of burns) ***Hypothyroidism following prolonged or extensive use of povidone iodine \u003cu\u003eReporting of suspected adverse reactions \u003c\/u\u003e Reporting suspected adverse reactions that occur after authorization of the medicinal product is important, as it allows continuous monitoring of the benefit\/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at: http:\/\/www.agenziafarmaco.gov.it\/content\/come-segnalare-una-sospetti-reazione-avversa.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn case of overdose, whether intentional or accidental (highly unlikely for vaginal pharmaceutical forms), hypothyroidism or hyperthyroidism may occur. Systemic absorption of iodine after repeated applications of the product on large wounds or severe burns can produce a series of symptoms such as: metallic taste, increased salivation, burning or stinging in the mouth and throat, irritation or swelling of the eyes, fever, skin rash, diarrhea and gastrointestinal disorders, hypotension, tachycardia, metabolic acidosis, hypernatremia, failure of renal function, pulmonary edema and shock. In case of accidental ingestion of large quantities of the product, institute a symptomatic and supportive treatment with particular attention to electrolyte balance and renal and thyroid function.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDuring pregnancy and breastfeeding, povidone iodine solution should be used only if strictly necessary and at the lowest possible dose, due to the ability of iodine to cross the placenta and be secreted into breast milk and the high sensitivity of the fetus and newborn to iodine. Furthermore, iodine is more concentrated in breast milk than in whey. The use of povidone iodine can cause transient hypothyroidism with increased TSH (thyroid stimulating hormone) in the fetus or newborn.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBetadine does not affect the ability to drive or use machines.\u003c\/p\u003e","brand":"Viatris Healthcare","offers":[{"title":"Default Title","offer_id":51131382563143,"sku":"023907025","price":17.21,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/viatris-healthcare-limited-betadine-10-concentrato-5-flaconi-140ml-5-fialoidi-10ml-5-canule-soluzione-vaginale-farmacia-dottor-tili-1213791704.jpg?v=1767144407"},{"product_id":"betadine-10-5-ml-10-flaconcini-soluzione-cutanea","title":"Betadine 10% 5 ml 10 vials cutaneous solution","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDisinfection and cleaning of damaged skin (small superficial wounds, bedsores with limited involvement of the epidermis).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBetadine 10% cutaneous solution 100 ml contain: \u003cu\u003eActive ingredient:\u003c\/u\u003e Povidone iodine (10% iodine) g 10 For the complete list of excipients, see section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% cutaneous solution: \u003c\/u\u003eGlycerol, Macrogol lauryl ether, Dibasic sodium phosphate dihydrate, Citric acid monohydrate, Sodium hydroxide, Purified water.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHypersensitivity to the active substance or to any of the excipients listed in paragraph 6.1. Hyperthyroidism Do not use in children under six months of age.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% cutaneous solution:\u003c\/u\u003e It is applied 2 times a day directly on small wounds and skin infections. A quantity of 5 ml of solution (containing 50 mg of iodine) is sufficient to treat an area of ​​approximately 15 cm on each side. For skin antisepsis: apply a protective layer of the brown solution until a medium intensity color is obtained: a non-staining surface film is formed.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% cutaneous solution\u003c\/u\u003e: Store at a temperature not exceeding 25°C\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor external use only. This medicine must not be applied to severely damaged skin and large surfaces. Do not use for prolonged treatments: use, especially if prolonged, may give rise to sensitization phenomena. In this case, treatment should be discontinued and a clinical evaluation performed. Particular caution should be used in patients with pre-existing renal insufficiency who require regular applications of Betadine on damaged skin (see section 5.2). Patients with goiter, thyroid nodules, or other acute and non-acute thyroid conditions are at risk of developing thyroid hyperfunction (hyperthyroidism) following administration of large amounts of iodine. In this patient population, povidone iodine solution should not be used for a prolonged period of time and on large body surfaces. Even after the end of treatment, it is necessary to look for early symptoms of possible hyperthyroidism and monitor thyroid function. Do not use at least 10 days before performing a scan or after a radioactive iodine scan or in the treatment of thyroid cancer with radioactive iodine. The pediatric population is at greater risk of developing hypothyroidism following applications of high doses of iodine. Due to the permeability of the skin and their high sensitivity to iodine, the use of povidone iodine should be reduced to the bare minimum in children. A check of the child's thyroid function (for example T4 and TSH levels) may be necessary. Any oral ingestion of povidone iodine by the child should be avoided. In pediatric age use only under strict supervision and in cases of actual need. Accidental ingestion or inhalation of some disinfectants can have serious, sometimes fatal consequences. Avoid contact with eyes.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAvoid the simultaneous use of other antiseptics and detergents. The polyvinylpyrrolidone-iodine complex is effective at pH values ​​between 2.0 and 7.0. It is possible that the complex reacts with proteins or other unsaturated organic compounds, and this leads to a reduction in its effectiveness. The concomitant use of preparations with enzymatic components for the treatment of wounds leads to a weakening of the effects of both substances. Povidone iodine should not be used simultaneously with products containing mercury salts or benzoin compounds, carbonates, tannic acid, alkali, hydrogen peroxide, taurolidine and silver. The use of povidone iodine-containing products concomitantly with other octedin-containing antiseptics in the same or adjacent sites may cause temporary dark discoloration of the affected areas. The oxidative effect of povidone iodine preparations can cause false positive results of some laboratory diagnostic tests (for example tests with toluidine or guaiac gum for the determination of hemoglobin or glucose in feces or urine). Avoid habitual use in patients receiving concomitant treatment with lithium. Absorption of iodine from povidone iodine solution may reduce thyroid iodine uptake. This may interfere with various tests (thyroid scan, determination of iodine-binding proteins, radioactive iodine diagnostics) and may make planned treatment of the thyroid with iodine (radioactive iodine therapy) impossible. After the end of treatment, an adequate period of time must pass before performing a new scan.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eUndesirable effects are classified according to their frequency: Very common (≥ 1\/10) Common (\u003e 1\/100 to \u003c 1\/10) Uncommon (≥ 1\/1,000 to \u003c 1\/100) Rare (≥ 1\/10,000 to \u003c 1\/1,000) Very rare (\u003c 1\/10,000) Not known (frequency cannot be estimated from the data available) \u003cu\u003eImmune system disorders\u003c\/u\u003e Rare: Hypersensitivity Very rare: Anaphylactic reaction \u003cu\u003eEndocrine disorders\u003c\/u\u003e Very rare: Hyperthyroidism* (sometimes with symptoms such as tachycardia or agitation) Not known: Hypothyroidism *** \u003cu\u003eMetabolism and nutrition disorders\u003c\/u\u003e Not known: Electrolyte imbalance **, Metabolic acidosis ** \u003cu\u003ePathologies of the skin and subcutaneous tissue\u003c\/u\u003e Rare: Contact dermatitis (with symptoms such as erythema, microvesicles and pruritus) Very rare: Angioedema Not known: Exfoliative dermatitis \u003cu\u003eRenal and urinary disorders\u003c\/u\u003e Not known: Acute renal failure **, Abnormal blood osmolarity ** *In patients with a history of thyroid disease (see section Warnings and special precautions for use) as a result of high iodine uptake, for example after long-term use of povidone iodine solution to treat wounds and burns on large skin areas. **May occur following the uptake of high quantities of povidone iodine (for example in the treatment of burns) ***Hypothyroidism following prolonged or extensive use of povidone iodine Reporting of suspected adverse reactions Reporting of suspected adverse reactions that occur after authorization of the medicinal product is important, as it allows continuous monitoring of the benefit\/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at: http:\/\/www.agenziafarmaco.gov.it\/content\/come-segnalare-una-sosp etta-reazione-avversa.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn case of overdose, whether intentional or accidental, hypothyroidism or hyperthyroidism may occur. Systemic absorption of iodine after repeated applications of the product on large wounds or severe burns may produce a number of symptoms such as: metallic taste, increased salivation, burning or stinging in the mouth and throat, irritation or swelling of the eyes, fever, skin rash, diarrhea and gastrointestinal disorders, hypotension, tachycardia, metabolic acidosis, hypernatremia, failure of renal function, pulmonary edema and shock. In case of accidental ingestion of large quantities of product, institute symptomatic and supportive treatment with particular attention to electrolyte balance and renal and thyroid function.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDuring pregnancy and breastfeeding, povidone iodine solution should be used only if strictly necessary and at the lowest possible dose, due to the ability of iodine to cross the placenta and be secreted into breast milk and the high sensitivity of the fetus and newborn to iodine. Furthermore, iodine is more concentrated in breast milk than in serum, therefore it can cause transient hypothyroidism with an increase in TSH (thyroid stimulating hormone) in the fetus or newborn\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBetadine does not affect the ability to drive or use machines.\u003c\/p\u003e","brand":"Viatris Healthcare","offers":[{"title":"Default Title","offer_id":51730210423111,"sku":"023907227","price":7.91,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/viatris-healthcare-limited-betadine-10-5-ml-10-flaconcini-soluzione-cutanea-farmacia-dottor-tili-1213791047.jpg?v=1767154871"},{"product_id":"betadine-10-30-g-gel","title":"Betadine 10% 30g gel","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% Cutaneous solution, alcoholic:\u003c\/u\u003e Disinfection and cleaning of damaged skin (small superficial wounds, bedsores with limited involvement of the epidermis). The medicine can be used to disinfect the skin before surgery. \u003cu\u003eBetadine 1% Mouthwash:\u003c\/u\u003e Disinfection of the oral mucosa. \u003cu\u003eBetadine 10% Gel:\u003c\/u\u003e Disinfection of damaged skin (small superficial wounds, bedsores with involvement limited to the epidermis). \u003cu\u003eBetadine 10% Impregnated gauzes:\u003c\/u\u003e Disinfection of damaged skin (small superficial wounds, bedsores with involvement limited to the epidermis).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% Cutaneous solution, alcoholic:\u003c\/u\u003e 100 ml contain: Active ingredient: Povidone iodine (10% iodine) 10 g. \u003cu\u003eBetadine 1% Mouthwash\u003c\/u\u003e: 100 ml contain: Active ingredient: Povidone iodine (10% iodine) 1.0 g. Excipient with known effects: ethanol \u003cu\u003eBetadine 10% Gel:\u003c\/u\u003e 100 g of gel or gel contains: Active ingredient: Povidone iodine (10% iodine) 10 g. \u003cu\u003eBetadine 10% Impregnated gauzes\u003c\/u\u003e 1 1 dm² gauze tablet of 3 g contains: Active ingredient: Povidone iodine (10% iodine) 0.25 g. For the full list of excipients, see section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% Cutaneous solution, alcoholic:\u003c\/u\u003e Isopropyl alcohol, Citric acid, Dibasic sodium phosphate, Purified water. \u003cu\u003eBetadine 10% Gel:\u003c\/u\u003e Polyethylene glycol 400, Polyethylene glycol 4000, Polyethylene glycol 6000, Purified water. \u003cu\u003eBetadine 1% Mouthwash:\u003c\/u\u003e Ethanol, Glycerol, Eucalyptol, Menthol, Sodium saccharin, Citric acid monohydrate, Dibasic sodium phosphate dihydrate, Potassium iodate Purified water. \u003cu\u003eBetadine 10% Impregnated gauzes:\u003c\/u\u003e Polyethylene glycol 400, Polyethylene glycol 4000, Polyethylene glycol 6000, Purified water.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e• Hypersensitivity to the active substance or to any of the excipients listed in paragraph 6.1. • Hyperthyroidism • Do not use in children under 6 months of age. • Mouthwash should not be used in children under 6 years of age.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% Cutaneous solution, alcoholic:\u003c\/u\u003e Apply undiluted Betadine alcohol solution once or twice to the entire skin area to be disinfected. Distribute the product with sterile gauze. Leave to dry completely. \u003cu\u003eBetadine 1% Mouthwash:\u003c\/u\u003e Dilute to your taste, only when necessary, keeping in mind that the effectiveness is maintained at the dilution of 1 part Betadine to 2 parts water, and gargle 2-3 times a day. DO NOT EXCEED THE RECOMMENDED DOSES. \u003cu\u003eBetadine 10% Gel:\u003c\/u\u003e Apply a light layer of gel 2 times a day as needed directly to the affected (small) area. DO NOT EXCEED THE RECOMMENDED DOSES. \u003cu\u003eBetadine 10% Impregnated gauzes:\u003c\/u\u003e Apply 1 gauze, 1-3 times a day. DO NOT EXCEED THE RECOMMENDED DOSES.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 1% Mouthwash\u003c\/u\u003e: Store at a temperature not exceeding 25°C. \u003cu\u003eBetadine 10% Cutaneous solution, alcoholic\u003c\/u\u003e: Store at a temperature not exceeding 25°C \u003cu\u003eBetadine 10% Gel and Betadine 10% Impregnated gauzes\u003c\/u\u003e: Store at a temperature not exceeding 30°C\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor external use only. The product must not be applied to severely damaged skin and large surfaces. Do not use for prolonged treatments: use, especially if prolonged, may give rise to sensitization phenomena. In this case, treatment should be discontinued and a clinical evaluation performed. Particular caution should be used in patients with pre-existing renal insufficiency who require regular applications of Betadine on damaged skin (see section 5.2). Patients with goiter, thyroid nodules, or other acute and non-acute thyroid conditions are at risk of developing thyroid hyperfunction (hyperthyroidism) following administration of large amounts of iodine. In this patient population, povidone iodine solution should not be used for a prolonged period of time and on large body surfaces. Even after the end of treatment, it is necessary to look for early symptoms of possible hyperthyroidism and monitor thyroid function. Do not use at least 10 days before performing a scan or after a radioactive iodine scan or in the treatment of thyroid cancer with radioactive iodine. The pediatric population is at greater risk of developing hypothyroidism following applications of high doses of iodine. Due to the permeability of the skin and their high sensitivity to iodine, the use of povidone iodine should be reduced to the bare minimum in children. A check of the child's thyroid function (for example, T4 and TSH levels) may be necessary. Any oral ingestion of povidone iodine by the child should be avoided. In pediatric age use only under strict supervision and in cases of actual need. Accidental ingestion or inhalation of some disinfectants can have serious, sometimes fatal, consequences. Avoid contact with eyes. \u003cu\u003eBetadine 10% cutaneous solution, alcoholic:\u003c\/u\u003e The alcohol solution is highly flammable: it must dry completely before any device (especially high-frequency surgical devices) is applied. In pre-operative preparation, avoid accumulation under the patient, as chemical burns to the skin may occur. Prolonged exposure to solution-related moist conditions may cause irritation or, rarely, severe skin reactions. If skin irritation, contact dermatitis or hypersensitivity occurs, discontinue use. Do not heat before application. \u003cu\u003eBetadine 1% mouthwash:\u003c\/u\u003e Care should be taken in case of oropharyngeal use to avoid inhalation of Betadine 1% mouthwash through the respiratory tract as it may cause complications such as pneumonia. This may particularly occur in intubated patients. Long-term use of povidone iodine for gargling should be avoided in pregnant women, breastfeeding mothers and people with a high risk of developing thyroid dysfunction due to excessive iodine intake (see sections 4.6 and 5.2). \u003ci\u003eImportant information about some excipients\u003c\/i\u003e Betadine 1% Mouthwash contains less than 1 mmol (23 mg) sodium per 20 ml of mouthwash, i.e. essentially 'sodium-free'. Betadine 1% Mouthwash contains 681.88 mg of alcohol (ethanol) in 20 ml of mouthwash. The amount in 20ml of this medicine is equivalent to less than 18ml of beer or 8ml of wine. The small amount of alcohol in this medicine will not produce any relevant effects.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAvoid the simultaneous use of other antiseptics and detergents. The polyvinylpyrrolidone-iodine complex is effective and stable at pH values ​​between 2.0 and 7.0. It is possible that the complex reacts with proteins or other unsaturated organic compounds, and this leads to a reduction in its effectiveness. The concomitant use of preparations with enzymatic components for the treatment of wounds leads to a weakening of the effects of both substances. Povidone iodine should not be used simultaneously with products containing mercury salts or benzonium compounds, carbonates, tannic acid, alkali, hydrogen peroxide, taurolidine and silver. The use of povidone iodine-containing products concomitantly with other octedin-containing antiseptics in the same or adjacent sites may cause temporary dark discoloration of the affected areas. The oxidative effect of povidone iodine preparations can cause false positive results of some laboratory diagnostic tests (for example tests with toluidine or guaiac gum for the determination of hemoglobin or glucose in feces or urine). Avoid routine use in patients receiving concomitant treatment with lithium. Absorption of iodine from povidone iodine solution may reduce thyroid iodine uptake. This may interfere with various tests (thyroid scan, determination of iodine-binding proteins, radioactive iodine diagnostics) and may make planned treatment of the thyroid with iodine (radioactive iodine therapy) impossible. After the end of treatment, an adequate period of time must pass before performing a new scan.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eUndesirable effects are classified according to their frequency: Very common (≥ 1\/10) Common (\u003e 1\/100 to \u003c 1\/10) Uncommon (≥ 1\/1,000 to \u003c 1\/100) Rare (≥ 1\/10,000 to \u003c 1\/1,000) Very rare (\u003c 1\/10,000) Not known (frequency cannot be estimated from the data available) \u003cu\u003eImmune system disorders \u003c\/u\u003e Rare Hypersensitivity Very rare Anaphylactic reaction \u003cu\u003eEndocrine disorders\u003c\/u\u003e Very rare Hyperthyroidism * (sometimes with symptoms such as tachycardia or agitation) Not known Hypothyroidism *** \u003cu\u003eMetabolism and nutrition disorders\u003c\/u\u003e Not known Electrolyte imbalance **, Metabolic acidosis ** \u003cu\u003eRespiratory, thoracic and mediastinal disorders \u003c\/u\u003e Not known Pneumonia ***** (only when using Betadine 1% mouthwash) \u003cu\u003ePathologies of the skin and subcutaneous tissue \u003c\/u\u003e Rare Contact dermatitis (with symptoms such as erythema, microvesicles and itching) Very rare Angioedema Not known Exfoliative dermatitis, Dry skin ^^ (only in case of use of Betadine 10% cutaneous solution, alcoholic) \u003cu\u003eRenal and urinary disorders\u003c\/u\u003e Not known Acute renal failure **, Abnormal blood osmolarity ** \u003cu\u003eInjury, poisoning and procedural complications\u003c\/u\u003e Not known Chemical skin burn ****, Thermal burn ^ (only in case of use of Betadine 10% cutaneous solution, alcoholic) *In patients with a history of thyroid pathologies (see paragraph Warnings and special precautions for use) following high iodine uptake, for example after long-term use of povidone-iodine solution for the treatment of wounds and burns on large skin areas. **May occur as a result of uptake of high quantities of povidone iodine (e.g. in the treatment of burns) ***Hypothyroidism following prolonged or extensive use of povidone iodine **** As a result of “accumulation” behind the patient during pre-operative preparation *****Complications due to inhalation - see section 4.4 ^Due to the high flammability, the alcoholic povidone iodine solution must dry completely before devices (particularly high-pressure surgical devices) can be used high frequency) ^^May occur after repeated applications due to the high alcohol content in the solution; the risk is greater for the genital area (for example for the scrotum) \u003cu\u003eReporting of suspected adverse reactions \u003c\/u\u003e Reporting suspected adverse reactions that occur after authorization of the medicinal product is important, as it allows continuous monitoring of the benefit\/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at: www.aifa.gov.it\/content\/segnalazioni-reazioni-avverse\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn case of overdose, whether intentional or accidental (highly unlikely for pharmaceutical forms such as gauze), hypothyroidism or hyperthyroidism may occur. Systemic absorption of iodine after repeated applications of the product on large wounds or severe burns can produce a series of symptoms such as: metallic taste, increased salivation, burning or stinging in the mouth and throat, irritation or swelling of the eyes, fever, skin rash, diarrhea and gastrointestinal disorders, hypotension, tachycardia, metabolic acidosis, hypernatremia, failure of renal function, pulmonary edema and shock. In case of accidental ingestion of large quantities of the product, institute a symptomatic and supportive treatment with particular attention to electrolyte balance and renal and thyroid function.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDuring pregnancy and breastfeeding, povidone iodine solution should be used only if strictly necessary and at the lowest possible dose, due to the ability of iodine to cross the placenta and be secreted into breast milk and the high sensitivity of the fetus and newborn to iodine. Furthermore, iodine is more concentrated in breast milk than in serum, therefore it can cause transient hypothyroidism with an increase in TSH (thyroid stimulating hormone) in the fetus or newborn.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBetadine does not affect the ability to drive or use machines.\u003c\/p\u003e","brand":"Viatris Healthcare","offers":[{"title":"Default Title","offer_id":51730211635527,"sku":"023907126","price":8.28,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/viatris-healthcare-limited-betadine-10-30-g-gel-farmacia-dottor-tili-1213791020.jpg?v=1767164829"},{"product_id":"betadine-10-125-ml-soluzione-vaginale","title":"Betadine 10% 125 ml vaginal solution","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDisinfectant of the vaginal mucosa.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e100 ml contain: \u003cu\u003eActive ingredient:\u003c\/u\u003e Povidone iodine (10% iodine) 10 g. For the full list of excipients, see section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDodecyl glucoside, macrogol lauryl ether, perfume for intimate hygiene, purified water.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e• Hypersensitivity to the active substance or to any of the excipients listed in paragraph 6.1. • Hyperthyroidism\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIrrigations: 2 tablespoons in 1\/2 l of warm water, 1 or 2 times a day - Do not exceed the recommended doses. Brushing on the cervix and vagina: use the pure product. After a reasonable period of time without appreciable results, consult your doctor.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eStore away from heat.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor external use only. Particular caution should be used in patients with pre-existing renal insufficiency who require regular applications of Betadine on damaged skin. Use of the product, especially if prolonged, can give rise to sensitization phenomena. In this case, stop treatment and adopt suitable therapeutic measures. Patients with goiter, thyroid nodules, or other acute and non-acute thyroid conditions are at risk of developing thyroid hyperfunction (hyperthyroidism) following administration of large amounts of iodine. In this patient population, povidone iodine solution should not be used for a prolonged period of time unless strictly indicated. Even after the end of treatment, early symptoms of possible hyperthyroidism should be looked for and, if necessary, thyroid function should be monitored. Do not use at least 10 days before performing a scan or after a radioactive iodine scan or in the treatment of thyroid cancer with radioactive iodine. The pediatric population is at greater risk of developing hypothyroidism following applications of high doses of iodine. Due to the permeability of the skin and their high sensitivity to iodine, the use of povidone iodine should be reduced to the bare minimum in children. A check of the child's thyroid function (for example T4 and TSH levels) may be necessary. Any oral ingestion of povidone iodine by the child should be avoided. In pediatric age use only under strict supervision and in cases of actual need. Accidental ingestion or inhalation of some disinfectants can have serious, sometimes fatal, consequences. Avoid contact with eyes.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAvoid the simultaneous use of other antiseptics and detergents. The polyvinylpyrrolidone-iodine complex is effective at pH values ​​between 2.0 and 7.0. It is possible that the complex reacts with proteins or other unsaturated organic compounds, and this leads to a reduction in its effectiveness. The concomitant use of preparations with enzymatic components for the treatment of wounds leads to a weakening of the effects of both substances. Povidone iodine should not be used simultaneously with products containing mercury salts or benzoin compounds, carbonates, tannic acid, alkali, hydrogen peroxide, taurolidine and silver. The use of povidone iodine-containing products concomitantly with other octedin-containing antiseptics in the same or adjacent sites may cause temporary dark discoloration of the affected areas. The oxidative effect of povidone iodine preparations can cause false positive results of some laboratory diagnostic tests (for example tests with toluidine or guaiac gum for the determination of hemoglobin or glucose in feces or urine). Avoid habitual use in patients receiving concomitant treatment with lithium. Absorption of iodine from povidone iodine solution may reduce thyroid iodine uptake. This may interfere with various tests (thyroid scan, determination of iodine-binding proteins, radioactive iodine diagnostics) and may make planned treatment of the thyroid with iodine (radioactive iodine therapy) impossible. After the end of treatment, an adequate period of time must pass before performing a new scan.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eUndesirable effects are classified according to their frequency: Very common (≥ 1\/10) Common (\u003e 1\/100 to \u003c 1\/10) Uncommon (≥ 1\/1,000 to \u003c 1\/100) Rare (≥ 1\/10,000 to \u003c 1\/1,000) Very rare (\u003c 1\/10,000) Not known (frequency cannot be estimated from the data available) \u003cu\u003eImmune system disorders\u003c\/u\u003e Rare: Hypersensitivity Very rare: Anaphylactic reaction \u003cu\u003eEndocrine disorders\u003c\/u\u003e Very rare: Hyperthyroidism* (sometimes with symptoms such as tachycardia or agitation) Not known: Hypothyroidism *** \u003cu\u003eMetabolism and nutrition disorders\u003c\/u\u003e Not known: Electrolyte imbalance **, Metabolic acidosis ** \u003cu\u003ePathologies of the skin and subcutaneous tissue\u003c\/u\u003e Rare: Contact dermatitis (with symptoms such as erythema, microvesicles and pruritus) Very rare: Angioedema \u003cu\u003eRenal and urinary disorders\u003c\/u\u003e Not known: Acute renal failure **, Abnormal blood osmolarity ** *In patients with a history of thyroid disease (see section Warnings and special precautions for use) as a result of high iodine uptake, for example after long-term use of povidone iodine solution to treat wounds and burns on large skin areas. **May occur following uptake of high amounts of povidone iodine (e.g. in the treatment of burns) ***Hypothyroidism following prolonged or extensive use of povidone iodine \u003cu\u003eReporting of suspected adverse reactions \u003c\/u\u003e Reporting suspected adverse reactions that occur after authorization of the medicinal product is important, as it allows continuous monitoring of the benefit\/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at: http:\/\/www.agenziafarmaco.gov.it\/content\/come-segnalare-una-sosp etta-reazione-avversa.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn case of overdose, whether intentional or accidental, hypothyroidism or hyperthyroidism may occur. Systemic absorption of iodine after repeated applications of the product on large wounds or severe burns may produce a number of symptoms such as: metallic taste, increased salivation, burning or stinging in the mouth and throat, irritation or swelling of the eyes, fever, skin rash, diarrhea and gastrointestinal disorders, hypotension, tachycardia, metabolic acidosis, hypernatremia, failure of renal function, pulmonary edema and shock. In case of accidental ingestion of large quantities of product, institute symptomatic and supportive treatment with particular attention to electrolyte balance and renal and thyroid function.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDuring pregnancy and breastfeeding, povidone iodine solution should be used only if strictly necessary and at the lowest possible dose, due to the ability of iodine to cross the placenta and be secreted into breast milk and the high sensitivity of the fetus and newborn to iodine. Furthermore, iodine is more concentrated in breast milk than in serum, therefore it can cause transient hypothyroidism with an increase in TSH (thyroid stimulating hormone) in the fetus or newborn.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBetadine does not affect the ability to drive or use machines.\u003c\/p\u003e","brand":"Viatris Healthcare","offers":[{"title":"Default Title","offer_id":51730211864903,"sku":"023907013","price":9.11,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/viatris-healthcare-betadine-10-125-ml-soluzione-vaginale-farmacia-dottor-tili-1254211094.jpg?v=1786730078"},{"product_id":"betadine-10-100-g-gel","title":"Betadine 10% 100 g gel","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% Cutaneous solution, alcoholic:\u003c\/u\u003e Disinfection and cleaning of damaged skin (small superficial wounds, bedsores with limited involvement of the epidermis). The medicine can be used to disinfect the skin before surgery. \u003cu\u003eBetadine 1% Mouthwash:\u003c\/u\u003e Disinfection of the oral mucosa. \u003cu\u003eBetadine 10% Gel:\u003c\/u\u003e Disinfection of damaged skin (small superficial wounds, bedsores with involvement limited to the epidermis). \u003cu\u003eBetadine 10% Impregnated gauzes:\u003c\/u\u003e Disinfection of damaged skin (small superficial wounds, bedsores with involvement limited to the epidermis).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% Cutaneous solution, alcoholic:\u003c\/u\u003e 100 ml contain: Active ingredient: Povidone iodine (10% iodine) 10 g. \u003cu\u003eBetadine 1% Mouthwash\u003c\/u\u003e: 100 ml contain: Active ingredient: Povidone iodine (10% iodine) 1.0 g. Excipient with known effects: ethanol \u003cu\u003eBetadine 10% Gel:\u003c\/u\u003e 100 g of gel or gel contains: Active ingredient: Povidone iodine (10% iodine) 10 g. \u003cu\u003eBetadine 10% Impregnated gauzes\u003c\/u\u003e 1 1 dm² gauze tablet of 3 g contains: Active ingredient: Povidone iodine (10% iodine) 0.25 g. For the full list of excipients, see section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% Cutaneous solution, alcoholic:\u003c\/u\u003e Isopropyl alcohol, Citric acid, Dibasic sodium phosphate, Purified water. \u003cu\u003eBetadine 10% Gel:\u003c\/u\u003e Polyethylene glycol 400, Polyethylene glycol 4000, Polyethylene glycol 6000, Purified water. \u003cu\u003eBetadine 1% Mouthwash:\u003c\/u\u003e Ethanol, Glycerol, Eucalyptol, Menthol, Sodium saccharin, Citric acid monohydrate, Dibasic sodium phosphate dihydrate, Potassium iodate Purified water. \u003cu\u003eBetadine 10% Impregnated gauzes:\u003c\/u\u003e Polyethylene glycol 400, Polyethylene glycol 4000, Polyethylene glycol 6000, Purified water.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e• Hypersensitivity to the active substance or to any of the excipients listed in paragraph 6.1. • Hyperthyroidism • Do not use in children under 6 months of age. • Mouthwash should not be used in children under 6 years of age.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 10% Cutaneous solution, alcoholic:\u003c\/u\u003e Apply undiluted Betadine alcohol solution once or twice to the entire skin area to be disinfected. Distribute the product with sterile gauze. Leave to dry completely. \u003cu\u003eBetadine 1% Mouthwash:\u003c\/u\u003e Dilute to your taste, only when necessary, keeping in mind that the effectiveness is maintained at the dilution of 1 part Betadine to 2 parts water, and gargle 2-3 times a day. DO NOT EXCEED THE RECOMMENDED DOSES. \u003cu\u003eBetadine 10% Gel:\u003c\/u\u003e Apply a light layer of gel 2 times a day as needed directly to the affected (small) area. DO NOT EXCEED THE RECOMMENDED DOSES. \u003cu\u003eBetadine 10% Impregnated gauzes:\u003c\/u\u003e Apply 1 gauze, 1-3 times a day. DO NOT EXCEED THE RECOMMENDED DOSES.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eBetadine 1% Mouthwash\u003c\/u\u003e: Store at a temperature not exceeding 25°C. \u003cu\u003eBetadine 10% Cutaneous solution, alcoholic\u003c\/u\u003e: Store at a temperature not exceeding 25°C \u003cu\u003eBetadine 10% Gel and Betadine 10% Impregnated gauzes\u003c\/u\u003e: Store at a temperature not exceeding 30°C\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor external use only. The product must not be applied to severely damaged skin and large surfaces. Do not use for prolonged treatments: use, especially if prolonged, may give rise to sensitization phenomena. In this case, treatment should be discontinued and a clinical evaluation performed. Particular caution should be used in patients with pre-existing renal insufficiency who require regular applications of Betadine on damaged skin (see section 5.2). Patients with goiter, thyroid nodules, or other acute and non-acute thyroid conditions are at risk of developing thyroid hyperfunction (hyperthyroidism) following administration of large amounts of iodine. In this patient population, povidone iodine solution should not be used for a prolonged period of time and on large body surfaces. Even after the end of treatment, it is necessary to look for early symptoms of possible hyperthyroidism and monitor thyroid function. Do not use at least 10 days before performing a scan or after a radioactive iodine scan or in the treatment of thyroid cancer with radioactive iodine. The pediatric population is at greater risk of developing hypothyroidism following applications of high doses of iodine. Due to the permeability of the skin and their high sensitivity to iodine, the use of povidone iodine should be reduced to the bare minimum in children. A check of the child's thyroid function (for example, T4 and TSH levels) may be necessary. Any oral ingestion of povidone iodine by the child should be avoided. In pediatric age use only under strict supervision and in cases of actual need. Accidental ingestion or inhalation of some disinfectants can have serious, sometimes fatal, consequences. Avoid contact with eyes. \u003cu\u003eBetadine 10% cutaneous solution, alcoholic:\u003c\/u\u003e The alcohol solution is highly flammable: it must dry completely before any device (especially high-frequency surgical devices) is applied. In pre-operative preparation, avoid accumulation under the patient, as chemical burns to the skin may occur. Prolonged exposure to solution-related moist conditions may cause irritation or, rarely, severe skin reactions. If skin irritation, contact dermatitis or hypersensitivity occurs, discontinue use. Do not heat before application. \u003cu\u003eBetadine 1% mouthwash:\u003c\/u\u003e Care should be taken in case of oropharyngeal use to avoid inhalation of Betadine 1% mouthwash through the respiratory tract as it may cause complications such as pneumonia. This may particularly occur in intubated patients. Long-term use of povidone iodine for gargling should be avoided in pregnant women, breastfeeding mothers and people with a high risk of developing thyroid dysfunction due to excessive iodine intake (see sections 4.6 and 5.2). \u003ci\u003eImportant information about some excipients\u003c\/i\u003e Betadine 1% Mouthwash contains less than 1 mmol (23 mg) sodium per 20 ml of mouthwash, i.e. essentially 'sodium-free'. Betadine 1% Mouthwash contains 681.88 mg of alcohol (ethanol) in 20 ml of mouthwash. The amount in 20ml of this medicine is equivalent to less than 18ml of beer or 8ml of wine. The small amount of alcohol in this medicine will not produce any relevant effects.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAvoid the simultaneous use of other antiseptics and detergents. The polyvinylpyrrolidone-iodine complex is effective and stable at pH values ​​between 2.0 and 7.0. It is possible that the complex reacts with proteins or other unsaturated organic compounds, and this leads to a reduction in its effectiveness. The concomitant use of preparations with enzymatic components for the treatment of wounds leads to a weakening of the effects of both substances. Povidone iodine should not be used simultaneously with products containing mercury salts or benzonium compounds, carbonates, tannic acid, alkali, hydrogen peroxide, taurolidine and silver. The use of povidone iodine-containing products concomitantly with other octedin-containing antiseptics in the same or adjacent sites may cause temporary dark discoloration of the affected areas. The oxidative effect of povidone iodine preparations can cause false positive results of some laboratory diagnostic tests (for example tests with toluidine or guaiac gum for the determination of hemoglobin or glucose in feces or urine). Avoid routine use in patients receiving concomitant treatment with lithium. Absorption of iodine from povidone iodine solution may reduce thyroid iodine uptake. This may interfere with various tests (thyroid scan, determination of iodine-binding proteins, radioactive iodine diagnostics) and may make planned treatment of the thyroid with iodine (radioactive iodine therapy) impossible. After the end of treatment, an adequate period of time must pass before performing a new scan.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eUndesirable effects are classified according to their frequency: Very common (≥ 1\/10) Common (\u003e 1\/100 to \u003c 1\/10) Uncommon (≥ 1\/1,000 to \u003c 1\/100) Rare (≥ 1\/10,000 to \u003c 1\/1,000) Very rare (\u003c 1\/10,000) Not known (frequency cannot be estimated from the data available) \u003cu\u003eImmune system disorders \u003c\/u\u003e Rare Hypersensitivity Very rare Anaphylactic reaction \u003cu\u003eEndocrine disorders\u003c\/u\u003e Very rare Hyperthyroidism * (sometimes with symptoms such as tachycardia or agitation) Not known Hypothyroidism *** \u003cu\u003eMetabolism and nutrition disorders\u003c\/u\u003e Not known Electrolyte imbalance **, Metabolic acidosis ** \u003cu\u003eRespiratory, thoracic and mediastinal disorders \u003c\/u\u003e Not known Pneumonia ***** (only when using Betadine 1% mouthwash) \u003cu\u003ePathologies of the skin and subcutaneous tissue \u003c\/u\u003e Rare Contact dermatitis (with symptoms such as erythema, microvesicles and itching) Very rare Angioedema Not known Exfoliative dermatitis, Dry skin ^^ (only in case of use of Betadine 10% cutaneous solution, alcoholic) \u003cu\u003eRenal and urinary disorders\u003c\/u\u003e Not known Acute renal failure **, Abnormal blood osmolarity ** \u003cu\u003eInjury, poisoning and procedural complications\u003c\/u\u003e Not known Chemical skin burn ****, Thermal burn ^ (only in case of use of Betadine 10% cutaneous solution, alcoholic) *In patients with a history of thyroid pathologies (see paragraph Warnings and special precautions for use) following high iodine uptake, for example after long-term use of povidone-iodine solution for the treatment of wounds and burns on large skin areas. **May occur as a result of uptake of high quantities of povidone iodine (e.g. in the treatment of burns) ***Hypothyroidism following prolonged or extensive use of povidone iodine **** As a result of “accumulation” behind the patient during pre-operative preparation *****Complications due to inhalation - see section 4.4 ^Due to the high flammability, the alcoholic povidone iodine solution must dry completely before devices (particularly high-pressure surgical devices) can be used high frequency) ^^May occur after repeated applications due to the high alcohol content in the solution; the risk is greater for the genital area (for example for the scrotum) \u003cu\u003eReporting of suspected adverse reactions \u003c\/u\u003e Reporting suspected adverse reactions that occur after authorization of the medicinal product is important, as it allows continuous monitoring of the benefit\/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at: www.aifa.gov.it\/content\/segnalazioni-reazioni-avverse\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn case of overdose, whether intentional or accidental (highly unlikely for pharmaceutical forms such as gauze), hypothyroidism or hyperthyroidism may occur. Systemic absorption of iodine after repeated applications of the product on large wounds or severe burns can produce a series of symptoms such as: metallic taste, increased salivation, burning or stinging in the mouth and throat, irritation or swelling of the eyes, fever, skin rash, diarrhea and gastrointestinal disorders, hypotension, tachycardia, metabolic acidosis, hypernatremia, failure of renal function, pulmonary edema and shock. In case of accidental ingestion of large quantities of the product, institute a symptomatic and supportive treatment with particular attention to electrolyte balance and renal and thyroid function.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDuring pregnancy and breastfeeding, povidone iodine solution should be used only if strictly necessary and at the lowest possible dose, due to the ability of iodine to cross the placenta and be secreted into breast milk and the high sensitivity of the fetus and newborn to iodine. Furthermore, iodine is more concentrated in breast milk than in serum, therefore it can cause transient hypothyroidism with an increase in TSH (thyroid stimulating hormone) in the fetus or newborn.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBetadine does not affect the ability to drive or use machines.\u003c\/p\u003e","brand":"Viatris Healthcare","offers":[{"title":"Default Title","offer_id":51730213601607,"sku":"023907138","price":14.79,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/viatris-healthcare-limited-betadine-10-100-g-gel-farmacia-dottor-tili-1213790997.jpg?v=1767156088"}],"url":"https:\/\/www.dottortili.com\/en\/collections\/betadine.oembed","provider":"Farmacia Dottor Tili","version":"1.0","type":"link"}