{"product_id":"tachipirina-bambini-10-supposte-250-mg","title":"Tachipirina Children 10 Suppositories 250 mg","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAs an antipyretic: symptomatic treatment of febrile diseases such as influenza, exanthematous diseases, acute respiratory tract diseases, etc. As an analgesic: headaches, neuralgia, myalgia and other medium-level painful manifestations of various origins.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e• Hypersensitivity to paracetamol or to any of the excipients listed in section 6.1. • Patients suffering from severe hemolytic anemia (this contraindication does not refer to the 500mg oral formulations). • Severe hepatocellular insufficiency (this contraindication does not refer to the 500mg oral formulations).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS AND PRECAUTIONS FOR USE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn rare cases of allergic reactions, administration must be suspended and appropriate treatment instituted. Use with caution in cases of chronic alcoholism, excessive alcohol intake (3 or more alcoholic drinks per day), anorexia, bulimia or cachexia, chronic malnutrition (low hepatic glutathione reserves), dehydration, hypovolemia. Paracetamol should be administered with caution to patients with mild to moderate hepatocellular insufficiency (including Gilbert's syndrome), severe hepatic insufficiency (Child-Pugh\u003e9), acute hepatitis, in concomitant treatment with drugs that alter liver function, glucose-6-phosphate dehydrogenase deficiency, hemolytic anemia. High or prolonged doses of the product can cause even serious alterations to the kidney and blood, therefore administration to subjects with renal insufficiency must be carried out only if actually necessary and under direct medical supervision. In case of prolonged use it is advisable to monitor liver and kidney function and blood count. During treatment with paracetamol, before taking any other medicine, check that it does not contain the same active ingredient, since if paracetamol is taken in high doses, serious adverse reactions may occur. Invite the patient to contact the doctor before combining any other drug. See also par. 4.5. \u003cb\u003e \u003cu\u003eImportant information about some excipients.\u003c\/u\u003e \u003c\/b\u003e \u003cu\u003eTachipirina 125 mg effervescent granules contains\u003c\/u\u003e \u003cu\u003e:\u003c\/u\u003e - \u003cb\u003easpartame\u003c\/b\u003e, is a source of phenylalanine. It can be harmful in case of phenylketonuria (deficiency of the enzyme phenylalanine hydroxylase) due to the risk linked to the accumulation of the amino acid phenylalanine. - \u003cb\u003emaltitol\u003c\/b\u003e: use with caution in patients suffering from rare hereditary problems of fructose intolerance. 70.6 mg of \u003cb\u003esodium\u003c\/b\u003e per sachet equivalent to 3.53% of the maximum daily intake recommended by WHO which corresponds to 2 g of sodium for an adult: to be taken into consideration in people with reduced kidney function or who follow a low-sodium diet. \u003cu\u003eTachipirina 500 mg effervescent granules contains:\u003c\/u\u003e - \u003cb\u003easpartame\u003c\/b\u003e, is a source of phenylalanine. It can be harmful in case of phenylketonuria (deficiency of the enzyme phenylalanine hydroxylase) due to the risk linked to the accumulation of the amino acid phenylalanine. - \u003cb\u003emaltitol\u003c\/b\u003e: use with caution in patients suffering from rare hereditary problems of fructose intolerance. - 283 mg of \u003cb\u003esodium\u003c\/b\u003e per sachet equivalent to 14.1% of the WHO recommended maximum daily intake which corresponds to 2 g of sodium for an adult. The maximum dose for this product is equivalent to 84.6% of the maximum daily sodium intake recommended by the WHO: to be taken into consideration in people with reduced kidney function or who follow a low-sodium diet.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eOral absorption of paracetamol depends on the speed of gastric emptying. Therefore, concomitant administration of drugs that slow (e.g. anticholinergics, opioids) or increase (e.g. prokinetics) the rate of gastric emptying may result in a decrease or increase in the bioavailability of the product, respectively. Concomitant administration of cholestyramine reduces the absorption of paracetamol. The simultaneous intake of paracetamol and chloramphenicol can induce an increase in the half-life of chloramphenicol, with the risk of increasing its toxicity. The concomitant use of paracetamol (4 g per day for at least 4 days) with oral anticoagulants can induce slight variations in INR values. In these cases, more frequent monitoring of INR values ​​should be conducted during concomitant use and after its discontinuation. Use with extreme caution and under strict control during chronic treatment with drugs that can cause the induction of hepatic monooxygenases or in case of exposure to substances that can have this effect (for example rifampicin, cimetidine, antiepileptics such as glutetimide, phenobarbital, carbamazepine). The same applies in cases of alcoholism and in patients treated with zidovudine. The administration of paracetamol can interfere with the determination of uric acid (using the phosphotungstic acid method) and with that of blood sugar (using the glucose-oxidase-peroxidase method).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBelow are the side effects of paracetamol organized according to the MedDRA systemic and organic classification. There is insufficient data to establish the frequency of the individual effects listed.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e \u003ci\u003ePathologies of the blood and lymphatic system\u003c\/i\u003e \u003c\/b\u003e | Thrombocytopenia, leukopenia, anemia, agranulocytosis\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e \u003ci\u003eImmune system disorders\u003c\/i\u003e \u003c\/b\u003e | Hypersensitivity reactions (urticaria, laryngeal edema, angioedema, anaphylactic shock)\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e \u003ci\u003eNervous system disorders\u003c\/i\u003e \u003c\/b\u003e | Dizziness\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e \u003ci\u003eGastrointestinal disorders\u003c\/i\u003e \u003c\/b\u003e | Gastrointestinal reaction\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e \u003ci\u003eHepatobiliary disorders\u003c\/i\u003e \u003c\/b\u003e | Abnormal liver function, hepatitis\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e \u003ci\u003ePathologies of the skin and subcutaneous tissue\u003c\/i\u003e \u003c\/b\u003e | Erythema multiforme, Stevens Johnson Syndrome, Epidermal necrolysis, rash\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e \u003ci\u003eRenal and urinary disorders\u003c\/i\u003e \u003c\/b\u003e | Acute renal failure, interstitial nephritis, hematuria, anuria\u003c\/p\u003e\n\u003cp\u003eVery rare cases of serious skin reactions have been reported. Reporting of suspected adverse reactions. Reporting suspected adverse reactions that occur after authorization of the medicine is important, as it allows continuous monitoring of the benefit\/risk balance of the medicine. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at https:\/\/www.aifa.gov.it\/content\/segnalazioni-reazioni-avverse.\u003c\/p\u003e","brand":"Angelini","offers":[{"title":"Default Title","offer_id":40207823994995,"sku":"012745042","price":6.5,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/angelini-tachipirina-bambini-10-supposte-250-mg-farmacia-dottor-tili-1258975883.jpg?v=1790944322","url":"https:\/\/www.dottortili.com\/en-eu\/products\/tachipirina-children-10-suppositories-250-mg","provider":"Farmacia Dottor Tili","version":"1.0","type":"link"}