{"product_id":"clin-4000-macrogol-senza-elettroliti-lassativo-osmotico-30-bustine-monouso-da-10-g","title":"Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g","description":"\u003cp\u003e\u003cstrong\u003eClin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g\u003c\/strong\u003e it's a \u003cstrong\u003emedical device\u003c\/strong\u003e ad \u003cstrong\u003elaxative action\u003c\/strong\u003e in \u003cstrong\u003e30 disposable sachets\u003c\/strong\u003e: each contains \u003cstrong\u003e10 g\u003c\/strong\u003e of \u003cstrong\u003emacrogol 4000\u003c\/strong\u003e and nothing else, because the formula does not have \u003cstrong\u003eexcipients\u003c\/strong\u003e, has no aromas and no sugars. It is used in \u003cstrong\u003echronic constipation\u003c\/strong\u003e and in cases of \u003cstrong\u003eoccasionally irregular bowel\u003c\/strong\u003e, and it is a macrogol \u003cstrong\u003ewithout electrolytes\u003c\/strong\u003e, which distinguishes it from most products of the same family.\u003c\/p\u003e\n\u003cp\u003eThe \u003cstrong\u003emacrogol 4000\u003c\/strong\u003e it is the only substance present, and it is worth knowing what that number means, because almost everyone reads it as a dosage and it is not. \u003cstrong\u003eMacrogol\u003c\/strong\u003e is the name that the \u003cstrong\u003eEuropean Pharmacopoeia\u003c\/strong\u003e gives to \u003cstrong\u003epolyethylene glycol\u003c\/strong\u003e, a polymer made of repeating units; the following number indicates the \u003cstrong\u003eaverage molecular weight\u003c\/strong\u003e of the espresso chain in \u003cstrong\u003edalton\u003c\/strong\u003e. Macrogol 4000 therefore means chains on average 4,000 daltons long: a large molecule, and the size is precisely the reason why it works the way it does. I \u003cstrong\u003e10 g\u003c\/strong\u003e of the sachet they are instead the quantity of substance, and they are the whole sachet.\u003c\/p\u003e\n\u003cp\u003eThe way he acts is \u003cstrong\u003ephysical\u003c\/strong\u003e, non-pharmacological, and you can feel the difference. Water molecules bind to the polymer to \u003cstrong\u003ehydrogen bond\u003c\/strong\u003e even before it reaches the intestine, and they remain attached: in the intestinal lumen the retained water increases the volume of the stool and softens its consistency. A \u003cstrong\u003eosmotic laxative\u003c\/strong\u003e as this does not affect the nerve plexuses of the wall or the muscles, which is what laxatives do instead \u003cstrong\u003estimulants\u003c\/strong\u003e or contact. The chain is too large to cross the mucosa, therefore \u003cstrong\u003eit is not absorbed\u003c\/strong\u003e, and is not a substrate for colon bacteria, therefore \u003cstrong\u003eit doesn't ferment\u003c\/strong\u003e: it is the reason why it does not produce the gas that accompanies sugar osmotics such as \u003cstrong\u003elactulose\u003c\/strong\u003e. \u003cstrong\u003eMacrogol 4000 is useful in cases of chronic constipation and occasionally irregular bowel movements.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe word \u003cstrong\u003ewithout electrolytes\u003c\/strong\u003e deserves its own line, because two different things with the same name coexist in the department. Different macrogols are formulated together with \u003cstrong\u003ego up\u003c\/strong\u003e (sodium, potassium, bicarbonate, chloride) which serve to maintain the balance of electrolytes when drinking a lot of liquid in one go: these are preparations designed for large volumes. \u003cstrong\u003eClin 4000\u003c\/strong\u003e it doesn't contain them: it just carries the polymer, and for this reason the powder doesn't have the salty taste that macrogols with electrolytes carry with them. It is also \u003cstrong\u003ewithout aroma\u003c\/strong\u003e, and this is not a shortcoming but the reason why it can be combined with any drink, from tea to broth to fruit juice, without changing its taste.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eClin 4000\u003c\/strong\u003e it's a \u003cstrong\u003emedical device\u003c\/strong\u003e in \u003cstrong\u003e30 disposable sachets\u003c\/strong\u003e, for \u003cstrong\u003e300 g\u003c\/strong\u003e total of macrogol 4000: the single-dose sachet avoids having to weigh the powder and the single wrapper remains closed until needed. The formula is \u003cstrong\u003esugar free\u003c\/strong\u003e, which matters to those keeping carbs under control, and it has no added excipients. In the same line there is the \u003cstrong\u003e200 g bottle\u003c\/strong\u003e with measuring spoon, the format that allows divided doses and is the one aimed at younger children: the MINSAN it looks a lot like the one in the sachets, so it's worth looking carefully at which one you're taking. Those looking for a pure macrogol, without salts and without flavourings, will find it in \u003cstrong\u003eClin 4000\u003c\/strong\u003e the most essential form.\u003c\/p\u003e\n\u003ch2\u003eINDICATIONS\u003c\/h2\u003e\n\u003ch3\u003eWhy should you use Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g? What is it for?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eClin 4000\u003c\/strong\u003e it's a \u003cstrong\u003emedical device\u003c\/strong\u003e ad \u003cstrong\u003elaxative action\u003c\/strong\u003e in \u003cstrong\u003e30 disposable sachets\u003c\/strong\u003e, each with \u003cstrong\u003e10 g\u003c\/strong\u003e of \u003cstrong\u003emacrogol 4000\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eIt is used in \u003cstrong\u003echronic constipation\u003c\/strong\u003e and in cases of \u003cstrong\u003eoccasionally irregular bowel\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003eThe \u003cstrong\u003emacrogol 4000\u003c\/strong\u003e it's a \u003cstrong\u003eosmotic laxative\u003c\/strong\u003e: retains water in the intestinal lumen and makes stool softer.\u003c\/p\u003e\n\u003ch2\u003eINGREDIENTS\u003c\/h2\u003e\n\u003ch3\u003eWhat ingredients does Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g contain?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eMacrogol 4000.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEach sachet contains \u003cstrong\u003e10 g of macrogol 4000\u003c\/strong\u003e. It contains no excipients or flavourings. Without sugar.\u003c\/p\u003e\n\u003ch2\u003eHOW TO USE\u003c\/h2\u003e\n\u003ch3\u003eHow do I use Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g?\u003c\/h3\u003e\n\u003cp\u003eDissolve the powder by mixing in any drink. The contents of one sachet (10 g) must be dissolved in at least \u003cstrong\u003e125ml\u003c\/strong\u003e (increase to 150 ml in pediatric age) of any drink, even hot, such as tea, herbal teas, milk, broth or fruit juice. The product does not alter the taste of the drink. Drink the reconstituted solution. It is recommended to take between meals.\u003c\/p\u003e\n\u003cp\u003eDue to its safety features, it allows for wide dosing flexibility.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAdults and children weighing more than 20 kg:\u003c\/strong\u003e 10 g (1 sachet), 1-3 times a day, according to individual response. To obtain a faster effect, the maximum daily dose (30 g) can be taken in a single administration. In case of prolonged use, the dose can be reduced to 10 g (1 sachet) 1-2 times a day, even every other day, preferably in the evening.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eChildren up to 20 kg:\u003c\/strong\u003e the dosage should be commensurate with body weight. We therefore recommend using the 200 g bottle of powder with measuring spoon, which allows you to customize the dose according to the child's real needs until soft stools are obtained. Do not exceed the maximum daily dosage of 30 g.\u003c\/p\u003e\n\u003ch2\u003eWARNINGS\u003c\/h2\u003e\n\u003ch3\u003eWhat are the warnings of Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g?\u003c\/h3\u003e\n\u003cp\u003eDo not take in case of: known hypersensitivity to macrogol; gastrointestinal perforation and\/or obstruction.\u003c\/p\u003e\n\u003cp\u003eDuring pregnancy and breastfeeding the product must be used upon medical prescription.\u003c\/p\u003e\n\u003cp\u003eThere are no known interactions with drugs, but it is advisable to take the product at least 2 hours apart from that of oral drugs.\u003c\/p\u003e\n\u003cp\u003eOccasionally abdominal distension and\/or nausea may be noted, which resolve with continued use. Rare cases of allergic reactions (rash, urticaria): in this case, suspend use of the product and inform your doctor or pharmacist.\u003c\/p\u003e\n\u003cp\u003eIn case of overdose, diarrhea may occur, which resolves spontaneously upon discontinuation of the product.\u003c\/p\u003e\n\u003ch2\u003eCONSERVATION\u003c\/h2\u003e\n\u003ch3\u003eHow is Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g stored?\u003c\/h3\u003e\n\u003cp\u003eStore in the original packaging \u003cstrong\u003ecool and dry place\u003c\/strong\u003e. The expiry date indicated refers to the product in intact packaging and correctly stored.\u003c\/p\u003e\n\u003cp\u003eThe manufacturer also declares, in the European registration of the device, to maintain the product \u003cstrong\u003ebelow 25 °C\u003c\/strong\u003e, in a dry place and away from direct sources of heat or light.\u003c\/p\u003e\n\u003ch2\u003eFORMAT\u003c\/h2\u003e\n\u003ch3\u003eWhat is the format of Clin 4000 Macrogol 4000 Without Electrolytes 30 Disposable Sachets of 10 g?\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e30 sachets of 10 g.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Shedir Pharma","offers":[{"title":"Default Title","offer_id":54137682493767,"sku":"931774119","price":21.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/shedir-pharma-srl-unipersonale-clin-4000-30bust-farmacia-dottor-tili-1244017616.jpg?v=1781241477","url":"https:\/\/www.dottortili.com\/en-eu\/products\/clin-4000-30-bags","provider":"Farmacia Dottor Tili","version":"1.0","type":"link"}