{"product_id":"benerva-300-mg-20-compresse-gastroresistenti","title":"Benerva 300 mg 20 gastro-resistant tablets","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eProphylaxis and treatment of vitamin B deficiency\u003csub\u003e1\u003c\/sub\u003e from increased demand or reduced absorption (beriberi and its various clinical forms). Deficient (ethyl) polyneuritis. Myocardiopathies of alcoholics. At high doses, adjuvant therapy of non-deficient neuritis and polyneuritis.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eBenerva 300 mg gastro-resistant tablets. \u003c\/i\u003e One tablet contains: thiamine hydrochloride (vitamin B\u003csub\u003e1\u003c\/sub\u003e) 300 mg. \u003ci\u003eBenerva 100 mg\/1 ml solution for injection for intramuscular use. \u003c\/i\u003e One 1 ml ampoule contains: thiamine hydrochloride (vitamin B\u003csub\u003e1\u003c\/sub\u003e) 100 mg. For the full list of excipients, see 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBenerva 300 mg gastro-resistant tablets:\u003c\/b\u003e Talc, povidone K90, magnesium stearate, methacrylic acid - ethyl acrylate copolymer (1:1), macrogol 6000, sodium carmellose. \u003cb\u003eBenerva 100 mg\/1 ml solution for injection for intramuscular use:\u003c\/b\u003e Phenol, glycerol, sodium dihydrogen phosphate dihydrate, sodium bicarbonate, water for injections.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eTablets\u003c\/i\u003e Known hypersensitivity to the active substance or to any of the excipients. \u003ci\u003eVials\u003c\/i\u003e Known or suspected hypersensitivity to the active substance or to any of the excipients.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eOral administration.\u003c\/i\u003e Mild and medium-severity cases: 100 mg every 24 hours. Severe cases: 600-1200 mg (2-4 Benerva 300 mg tablets) per day for 1-2 weeks, then 300 mg (1 Benerva 300 mg tablet) per day for several weeks. High-dose Benerva tablets (300 mg) allow you to establish an intensive treatment. \u003ci\u003eParenteral administration.\u003c\/i\u003e Parenteral administration is reserved for cases with impaired intestinal absorption, as well as in the initial treatment of acute deficiencies, accompanied by polyneuritis, mental and cardiac disorders, in particular in chronic alcoholism: 50-200 mg i.m. per day.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eTablets\u003c\/i\u003e Store in the original packaging. \u003ci\u003eVials\u003c\/i\u003e Store at temperatures below 25°C, in the original packaging, protected from light.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVitamin B preparations\u003csub\u003e1\u003c\/sub\u003e or derivatives, especially parenterally, can cause disorders in subjects who have had sensitization phenomena or pathological manifestations due to allergies. The risk of hypersensitivity reactions is increased with repeated intramuscular administration. Oral administration is therefore preferable, where possible.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThiosemicarbazone and 5-fluorouracil inhibit the activity of thiamine. Interferences with laboratory tests: • vitamin B\u003csub\u003e1\u003c\/sub\u003e can give false positives in the determination of urobilinogen with the Ehrlich reagent; • high doses of vitamin B\u003csub\u003e1\u003c\/sub\u003e may interfere with the spectrophotometric determination of serum theophylline.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe side effects reported below derive from spontaneous reports and it is therefore not possible to classify them into frequency categories. \u003ci\u003eTablets\u003c\/i\u003e. \u003cu\u003eImmune system disorders\u003c\/u\u003e: Allergic and anaphylactic reactions have been reported in individual cases, with symptoms such as pruritus, urticaria, angioedema, abdominal pain, breathing difficulties, tachycardia, palpitations and shock. \u003cu\u003eGastrointestinal disorders\u003c\/u\u003e: Mild gastrointestinal disorders such as nausea, vomiting, diarrhea and abdominal pain have been reported. \u003ci\u003eVials\u003c\/i\u003e. \u003cu\u003eSystemic pathologies and conditions relating to the administration site\u003c\/u\u003e: Pain at the injection site. \u003cu\u003eImmune system disorders\u003c\/u\u003e: Allergic and anaphylactic reactions with symptoms such as pruritus, urticaria, angioedema, abdominal pain, breathing difficulties, tachycardia, palpitations and shock have been reported, usually after intravenous, intramuscular or subcutaneous injection. These reactions are often preceded by sneezing or transient itching.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eTablets\u003c\/i\u003e No cases of overdose have been reported. \u003ci\u003eVials\u003c\/i\u003e Isolated clinical cases of toxic reactions to prolonged parenteral administration of thiamine probably represent hypersensitivity reactions.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThis product is not indicated for use during pregnancy or breastfeeding.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNo negative effects of the preparation on these activities have been reported or expected. However, patients should be advised to observe their reactions to the drug before driving or operating machinery.\u003c\/p\u003e","brand":"Teofarma","offers":[{"title":"Default Title","offer_id":51730203410759,"sku":"004642031","price":10.6,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/teofarma-benerva-300-mg-20-compresse-gastroresistenti-farmacia-dottor-tili-1258975891.jpg?v=1790944399","url":"https:\/\/www.dottortili.com\/en-eu\/products\/benerva-300-mg-20-gastroresistent-tablets","provider":"Farmacia Dottor Tili","version":"1.0","type":"link"}