{"title":"Farmaci e Trattamenti per Herpes Labiale","description":"\u003cp\u003eTrattamenti per l'herpes labiale, dal primo formicolio alla crosta: creme antivirali con aciclovir e penciclovir, cerotti idrocolloidali che coprono e proteggono la vescicola, stick labbra lenitivi e riparatori. Da applicare ai primi sintomi per accorciare la durata dell'episodio. Spedizione veloce in 24\/48 ore.\u003c\/p\u003e","products":[{"product_id":"zoviraxlabiale-5-crema-2g","title":"Zoviraxlabiale 5% cream 2g","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eZOVIRAXLABIALE 5% cream is indicated in the treatment of herpes simplex virus infections of the lips (\u003ci\u003eherpes labialis\u003c\/i\u003e recurrent) in adults and adolescents (over 12 years of age).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eOne gram of cream contains: Active ingredient: Aciclovir 50 mg. Excipients with known effects: cetostearyl alcohol, sodium lauryl sulfate, propylene glycol. \u003cb\u003eFor the complete list of excipients see section 6.1.\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePoloxamer 407, \u003cb\u003eCetostearyl alcohol\u003c\/b\u003e, \u003cb\u003eSodium lauryl sulfate\u003c\/b\u003e, White Vaseline, Liquid Paraffin, Arlacel 165, Dimethicone 20, \u003cb\u003ePropylene glycol\u003c\/b\u003e, Purified water.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHypersensitivity to the active substance, to valaciclovir, or to any of the excipients. Children under 12 years old.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTopical use. \u003ci\u003eAdults and adolescents over 12 years of age:\u003c\/i\u003e ZOVIRAXLABIALE 5% cream must be applied 5 times a day at intervals of approximately 4 hours, omitting the night application. ZOVIRAXLABIALE 5% cream must be applied as early as possible, preferably during the earliest phases (prodromes or erythema). However, treatment can also be started in the later stages (papules or vesicles). Treatment must continue for at least 4 days. If there is no healing, treatment can continue for up to a maximum of 10 days. If the lesions are still present after 10 days, it is advisable for patients to consult their doctor. Patients should wash their hands before and after applying the cream and avoid unnecessary rubbing of the lesions or touching them with a towel in order to avoid worsening or transmission of the infection. \u003ci\u003eChildren under the age of 12\u003c\/i\u003e: The safety and efficacy of ZOVIRAXLABIALE have not been studied in patients under 12 years of age. \u003ci\u003ePatients with renal or hepatic insufficiency\u003c\/i\u003e: Aciclovir is eliminated mainly via the kidneys, but systemic absorption of aciclovir after topical application is negligible. Consequently, no dose modification is required in patients with renal or hepatic impairment (see \u003ci\u003ePharmacokinetic properties\u003c\/i\u003e).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eStore at a temperature not exceeding 25°C. Do not refrigerate.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eZOVIRAXLABIALE 5% cream should only be used for cold sores present on the mouth. Application to mucous membranes such as those of the mouth and eyes is not recommended and should not be used in the treatment of genital herpes. Particular care should be taken to avoid accidental application into the eyes. It is recommended that people with particularly severe forms of recurrent cold sores consult their doctor. The use of the product, especially if prolonged, can give rise to sensitization phenomena: if this happens, treatment should be stopped and the doctor should be consulted. It is recommended that those who suffer from cold sores avoid transmitting the virus, especially when active lesions are present (for example by washing their hands before and after applying the cream, see \u003ci\u003eDosage and method of administration\u003c\/i\u003e). The use of ZOVIRAXLABIALE 5% cream in immunocompromised patients is not recommended. It is recommended that such patients consult their doctor regarding the treatment of any infection. \u003cb\u003e \u003cu\u003eImportant information about some excipients:\u003c\/u\u003e \u003c\/b\u003e ZOVIRAXLABIALE 5% cream contains propylene glycol, cetostearyl alcohol, sodium lauryl sulphate. This medicinal product contains 200 mg of propylene glycol per dose equivalent to 400 mg\/g. This medicine contains cetostearyl alcohol. May cause localized skin reactions (e.g. contact dermatitis). This medicinal product contains 3.75 mg sodium lauryl sulphate per dose equivalent to 7.5 mg\/g. Sodium lauryl sulfate may cause skin irritation (stinging or burning sensation) or intensify skin reactions caused by other medicines when applied to the same area.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNo clinically significant interactions have been identified.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe side effects reported for ZOVIRAXLABIALE 5% cream are listed according to the following convention on the frequency of occurrence: very common: ≥ 1\/10, common: ≥ 1\/100 and \u003c 1\/10, uncommon: ≥ 1\/1000 and \u003c 1\/100, rare: ≥ 1\/10000 and \u003c 1\/1000, very rare: \u003c1\/10000, not known (frequency cannot be estimated from the available data). \u003cb\u003ePathologies of the skin and subcutaneous tissue\u003c\/b\u003e. \u003cu\u003eUncommon\u003c\/u\u003e: • transient burning or pain after application of ZOVIRAXLABIALE 5% cream, • moderate dryness or flaking of the skin, • itching; \u003cu\u003eRare\u003c\/u\u003e: • erythema, • contact dermatitis following application. Where sensitivity tests were conducted, it was shown that the substances causing reactivity phenomena were the components of the base cream rather than aciclovir.\u003cb\u003eImmune system disorders\u003c\/b\u003e. \u003cu\u003eVery rare\u003c\/u\u003e: • immediate hypersensitivity including angioedema and urticaria. \u003cu\u003eReporting of suspected adverse reactions\u003c\/u\u003e. Reporting suspected adverse reactions that occur after authorization of the medicine is important, as it allows continuous monitoring of the benefit\/risk balance of the medicine. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at: https:\/\/www.aifa.gov.it\/content\/segnalazioni-reazioni-avverse.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eZOVIRAXLABIALE 5% cream is a preparation for topical use. Even if the entire contents of a 2 g cream pack of ZOVIRAXLABIALE 5% cream are ingested or applied topically, no undesirable effects should be expected. In case of suspected overdose, the patient should consult his doctor.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eFertility\u003c\/b\u003e: No data are available regarding the effects of aciclovir in oral or i.v. formulation. for infusion on fertility in women. In a study of 20 male patients with normal sperm counts, aciclovir administered orally at doses of up to 1 gram per day for up to 6 months was shown to have no effect on the number, morphology and motility of sperm in men. \u003cb\u003ePregnancy\u003c\/b\u003e: You should consider using ZOVIRAXLABIALE 5% cream only if the potential benefits outweigh the possibility of unknown risks. However, the systemic exposure to aciclovir following topical application of aciclovir cream is very low. A post-marketing registry on the use of aciclovir in pregnancy provided data on pregnancy outcomes in women exposed to various formulations of aciclovir. These observations did not show an increase in the number of birth defects among subjects exposed to aciclovir compared to the general population and all birth defects did not show any particularity or common characteristics, such as to suggest a single cause. Systemic exposure to aciclovir following topical application of aciclovir cream is very low. \u003cb\u003eBreastfeeding\u003c\/b\u003e: Although some data indicate that aciclovir passes into breast milk following systemic administration, the dose that an infant receives following use of ZOVIRAXLABIALE 5% cream in the mother should be insignificant. During pregnancy and breastfeeding, ZOVIRAXLABIALE 5% cream must be used only after consulting your doctor and evaluating with him the risk\/benefit ratio in the individual case.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eZOVIRAXLABIALE 5% cream is unlikely to have any effect on the ability to drive and use machines.\u003c\/p\u003e","brand":"Haleon","offers":[{"title":"Default Title","offer_id":51131289043271,"sku":"037868015","price":9.72,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/haleon-italy-srl-zoviraxlabiale-5-crema-2g-farmacia-dottor-tili-1213792227.jpg?v=1767134111"},{"product_id":"herpesun-defend-stick-labbra-5ml","title":"Herpesun Defend lip stick 5ml","description":"\u003cp\u003eThe \u003cstrong\u003eHerpesun Defend lip stick 5ml\u003c\/strong\u003e is a medical device designed to offer effective protection against cold sores, particularly when exposed to sunlight or tanning lamps. This lip stick is specifically formulated to prevent the onset of\u003cstrong\u003e herpes caused by ultraviolet radiation\u003c\/strong\u003e, thanks to its ability to effectively shield UVA and UVB rays. \u003cspan\u003e It guarantees one\u003cstrong\u003e lip protection with sun protection factor (SPF) of 20 \u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eIts composition includes a mix of plant-derived extracts and oils, which not only protect, but also \u003cstrong\u003ethey hydrate \u003c\/strong\u003eand they favor the \u003cstrong\u003ereepithelialization of the lips\u003c\/strong\u003e. Among the key ingredients we find jojoba oil, known for its hydrating and soothing properties, and other components that help keep lips soft and protected. This stick is ideal for those looking for a hypoallergenic, high-quality product that guarantees optimal sun protection and effective prevention of cold sores.\u003c\/p\u003e\n\u003cp\u003eThanks to its advanced formulation, the \u003cstrong\u003eHerpesun Defend lip stick\u003c\/strong\u003e it is an indispensable ally for those who want to keep their lips healthy and protected during sun exposure. Its practicality of use makes it perfect to always carry with you, ensuring continuous protection and deep hydration at any time of the day.\u003c\/p\u003e\n\u003cbr\u003e\u003ch2\u003eINDICATIONS\u003c\/h2\u003e\n\u003ch3\u003eWhy use Herpesun Defend lip stick 5ml? What is it for?\u003c\/h3\u003e\u003cp\u003eMedical device lip stick with SPF 20 sun protection, indicated to prevent the onset of cold sores triggered by exposure to UVA and UVB rays; hydrates the lips and promotes their re-epithelization.\u003c\/p\u003e\n\u003cbr\u003e\u003ch2\u003eINGREDIENTS\u003c\/h2\u003e\n\u003ch3\u003eWhat ingredients does Herpesun Defend lip stick 5ml contain?\u003c\/h3\u003e\u003cp\u003eParaffinum Liquidum, Hydrogenated Microcrystalline Wax, Ethylhexyl Methoxycinnamate, Copernicia Cerifera Wax, Butyl Methoxydibenzoylmethane, Behenyl Alcohol, Zinc Oxide, Hydroxyapatite, Propylene Glycol, Echinacea Angustifolia Extract, Simmondsia Chinensis Seed Oil, Bisabolol, Escin, Beta-Sitosterol, Phospholipids, Citronellol, Geraniol, Glycyrrhetinic Acid, Benzoic Acid.\u003c\/p\u003e\n\u003cbr\u003e\u003ch2\u003eHOW TO USE\u003c\/h2\u003e\n\u003ch3\u003eHow do I use Herpesun Defend lip stick 5ml?\u003c\/h3\u003e\u003cp\u003eGently apply a light film of product to the lips, up to a maximum of 10 times a day.\u003c\/p\u003e\n\u003cbr\u003e\u003ch2\u003eWARNINGS\u003c\/h2\u003e\n\u003ch3\u003eWhat are the warnings of Herpesun Defend lip stick 5ml?\u003c\/h3\u003e\u003cp\u003eExternal use. Keep out of reach of children. Do not use if package is open or damaged. Don't stay exposed to the sun for too long even if you use a sunscreen product.\u003c\/p\u003e\n\u003cbr\u003e\u003ch2\u003eCONSERVATION\u003c\/h2\u003e\n\u003ch3\u003eHow is Herpesun Defend lip stick 5ml stored?\u003c\/h3\u003e\u003cp\u003eStore the product in a cool, dry place.\u003cbr\u003eKeep away from heat sources.\u003cbr\u003ePost-opening validity: 6 months.\u003c\/p\u003e\n\u003cbr\u003e\u003ch2\u003eFORMAT\u003c\/h2\u003e\n\u003ch3\u003eWhat is the format of Herpesun Defend lip stick 5ml?\u003c\/h3\u003e\u003cp\u003e5 ml stick.\u003c\/p\u003e","brand":"Alfasigma","offers":[{"title":"Default Title","offer_id":51131345502535,"sku":"988143487","price":9.79,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/alfasigma-spa-herpesun-defend-stick-labbra-5ml-farmacia-dottor-tili-1213791995.webp?v=1767149448"},{"product_id":"compeed-herpes-labiale-15-pezzi","title":"Compeed cold sores 15 pieces","description":"\u003cp\u003eThe \u003cstrong\u003eCompeed cold sores 15 pieces\u003c\/strong\u003e is an innovative treatment designed to offer a \u003cstrong\u003equick relief\u003c\/strong\u003e and one \u003cstrong\u003efast healing\u003c\/strong\u003e of lesions caused by cold sores. Each patch is made with a \u003cstrong\u003ehydrocolloid technology\u003c\/strong\u003e advanced that creates an ideal moist environment for healing, reducing the risk of scabbing and accelerating the healing process.\u003c\/p\u003e\n\n\u003cp\u003eThese \u003cstrong\u003etransparent plasters\u003c\/strong\u003e they act as one \u003cstrong\u003esecond skin\u003c\/strong\u003e, offering discreet and continuous protection for up to 12 hours. Their adhesiveness guarantees a secure hold, while the possibility of applying make-up or lipstick over the patch makes them perfect for daily use. Furthermore, they act as \u003cstrong\u003eshield against the virus\u003c\/strong\u003e, helping to reduce the risk of further infections.\u003c\/p\u003e\n\n\u003cp\u003eThe Compeed cold sore is easy to apply and offers a \u003cstrong\u003eimmediate relief from burning and itching\u003c\/strong\u003e, improving comfort throughout the entire healing cycle. For best results, it is recommended to apply the patch at the first signs of a rash, such as tingling, and to continue use day and night until the blister is completely healed. The pack contains 15 patches, ensuring a practical and long-lasting solution for managing cold sores.\u003c\/p\u003e\n\u003cbr\u003e\u003ch2\u003eINDICATIONS\u003c\/h2\u003e\n\u003ch3\u003eWhy do you use Compeed cold sores 15 pieces? What is it for?\u003c\/h3\u003e\u003cp\u003eMedical device patch with hydrocolloid technology, indicated for the treatment of cold sore lesions; creates a moist environment that promotes healing by reducing the formation of crusts, offers discreet protection for up to 12 hours and immediate relief from burning and itching.\u003c\/p\u003e\n\u003cbr\u003e\u003ch2\u003eHOW TO USE\u003c\/h2\u003e\n\u003ch3\u003eHow do I use Compeed cold sores 15 pieces?\u003c\/h3\u003e\u003cp\u003eSee the leaflet inside for tips on treating herpes.\u003c\/p\u003e\n\u003cbr\u003e\u003ch2\u003eWARNINGS\u003c\/h2\u003e\n\u003ch3\u003eWhat are the warnings of Compeed cold sores 15 pieces?\u003c\/h3\u003e\u003cp\u003eEach patch is transparent and creates an ideal environment for healing as well as lasting up to 12 hours (individual experiences may vary: in a clinical study of 174 subjects, in 25% of cases the patch lasted at least 12 hours). It acts as a shield against the virus, reducing the risk of further infection caused by the injury. You can apply make-up or lipstick on the patch. For best results the patch should be applied at the first signs of a rash such as tingling. While the virus is active, continue to use the patch day and night until the herpes blister is completely healed.\u003c\/p\u003e\n\u003cbr\u003e\u003ch2\u003eCONSERVATION\u003c\/h2\u003e\n\u003ch3\u003eHow do you store Compeed cold sores 15 pieces?\u003c\/h3\u003e\u003cp\u003eValidity with intact packaging: 24 months.\u003c\/p\u003e\n\u003cbr\u003e\u003ch2\u003eFORMAT\u003c\/h2\u003e\n\u003ch3\u003eWhat is the size of Compeed cold sores 15 pieces?\u003c\/h3\u003e\u003cp\u003ePack of 15 patches.\u003c\/p\u003e","brand":"Perrigo","offers":[{"title":"Default Title","offer_id":51131345764679,"sku":"979605488","price":16.73,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/perrigo-italia-srl-compeed-herpes-labiale-15-pezzi-farmacia-dottor-tili-1213791992.jpg?v=1767149470"},{"product_id":"vectavir-1-crema-2g","title":"Vectavir 1% cream 2g","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVectavir is indicated for the treatment of herpes labialis.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEach gram of cream contains 10 mg of penciclovir. Excipients with known effects: 77.2 mg of cetostearyl alcohol, 416.8 mg of propylene glycol. For the full list of excipients, see section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSolid paraffin, Liquid paraffin, Cetostearyl alcohol, Propylene glycol, Cetomacrogol 1000, Purified water.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHypersensitivity to the active substance penciclovir, to famciclovir or to any of the excipients listed in section 6.1. Children under the age of 12.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ci\u003eAdults (including the elderly) and children over 12 years of age: \u003c\/i\u003e VECTAVIR should be applied at intervals of approximately 2 hours throughout the day. Treatment, to be continued for 4 days, should be started as soon as possible, at the first sign of infection. However, even in patients who start therapy later, VECTAVIR has proven effective in accelerating the healing of lesions, reducing the pain associated with them and shortening the time for viral spread. \u003cu\u003eApplication instructions\u003c\/u\u003e: VECTAVIR must be applied, in an amount suitable for the size of the area to be treated, with a clean finger or with a disposable applicator which must be discarded after use [\u003ci\u003efor packages containing applicators\u003c\/i\u003e]. \u003ci\u003ePediatric population \u003c\/i\u003e. \u003ci\u003eChildren (under 12 years of age)\u003c\/i\u003e: Vectavir is not recommended for use in children under 12 years of age due to a lack of data on safety and\/or efficacy.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDo not store above 30°C. Do not freeze.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe cream should only be applied to lesions on the lips and around the mouth. Application to mucous membranes (e.g. in the eyes, mouth or nose or on the genitals) is not recommended. Particular care should be taken to avoid application in or near the eyes. Severely immunocompromised patients (e.g. patients with AIDS or bone marrow transplant recipients) should be encouraged to consult a physician if oral therapy is indicated. Vectavir contains cetostearyl alcohol: it may cause local skin reactions (e.g. contact dermatitis). Vectavir contains 416 mg of propylene glycol in each gram of cream: may cause skin irritation.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eExperience in clinical trials has not identified interactions resulting from the concomitant administration of drugs for topical or systemic use and Vectavir cream.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVectavir cream was well tolerated during studies in humans. Experience from clinical trials has shown that there is no difference in the frequency or type of adverse reactions between Vectavir cream and placebo. The most common events are adverse events in the application area. Adverse reactions are listed below by system organ class, class and frequency. The frequencies are defined as follows: \u003ci\u003every common\u003c\/i\u003e (\u0026gt;1\/10); \u003ci\u003ecommon\u003c\/i\u003e (\u003e1\/100 to \u003c1\/10); \u003ci\u003euncommon\u003c\/i\u003e (\u003e1\/1,000 to \u003c1\/100); \u003ci\u003erare\u003c\/i\u003e (\u003e1\/10,000 to \u003c1\/1,000); \u003ci\u003every rare\u003c\/i\u003e (\u0026lt;1\/10.000), \u003ci\u003enot known\u003c\/i\u003e (frequency cannot be estimated from the available data). Within each frequency class, undesirable effects are presented in order of decreasing seriousness.\u003c\/p\u003e\n\u003cp\u003eSystemic pathologies and conditions relating to the administration site.\u003c\/p\u003e\n\u003cp\u003eCommon: Application site reactions (including skin burning sensation, skin pain, hypoesthesia).\u003c\/p\u003e\n\u003cp\u003ePost-marketing surveillance highlighted the following adverse events (all reactions were either localized or general). It is difficult to define a frequency for post-marketing adverse events and therefore events are listed with an unknown frequency.\u003c\/p\u003e\n\u003cp\u003eImmune system disorders: Hypersensitivity, urticaria.\u003c\/p\u003e\n\u003cp\u003eSkin and subcutaneous tissue disorders: Allergic dermatitis (including rash, pruritus, blisters and edema).\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eReporting of suspected adverse reactions\u003c\/u\u003e. Reporting suspected adverse reactions that occur after authorization of the medicine is important, as it allows continuous monitoring of the benefit\/risk balance of the medicine. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at: http:\/\/www.agenziafarmaco.gov.it\/content\/come-segnalare-una-sospetti-reazione-avversa.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEven after oral ingestion of the entire contents of a pack of VECTAVIR cream, no side effects should occur; penciclovir is poorly absorbed after oral administration. However, irritation of the oral cavity may occur. In case of accidental ingestion, no specific treatment is necessary.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePregnancy\u003c\/b\u003e: When the cream is used in pregnant women, there is unlikely to be any cause for concern about adverse effects as systemic absorption of penciclovir following topical application of Vectavir cream was found to be minimal (see section 5.2). As the safety of penciclovir in pregnant women has not been established, Vectavir cream should be used, on the advice of a doctor, during pregnancy or by mothers who are breastfeeding, only if the potential benefits outweigh the potential risks associated with treatment. \u003cb\u003eBreastfeeding:\u003c\/b\u003e When the cream is used in women who are breastfeeding, there is unlikely to be any cause for concern about adverse effects as systemic absorption of penciclovir following topical application of Vectavir cream has been found to be minimal (see section 5.2). There is no information on the excretion of penciclovir in human milk.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVectavir does not affect the ability to drive or use machines.\u003c\/p\u003e","brand":"Perrigo","offers":[{"title":"Default Title","offer_id":51131372601671,"sku":"032155018","price":13.48,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/perrigo-italia-srl-vectavir-1-crema-2g-farmacia-dottor-tili-1213791865.jpg?v=1767137608"},{"product_id":"vectavir-labiale-1-2-g-crema","title":"Vectavir labial 1% 2 g cream","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVECTAVIR LABIALE is indicated for the treatment of herpes labialis.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEach gram of cream contains 10 mg of penciclovir. Excipients with known effects: 77.2 mg of cetostearyl alcohol, 416 mg of propylene glycol. For the full list of excipients, see section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSolid paraffin Liquid paraffin Cetostearyl alcohol Propylene glycol Cetomacrogol 1000 Red iron oxide (E-172) Yellow iron oxide (E-172) Purified water\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHypersensitivity to the active substance, to famciclovir or to any of the excipients listed in section 6.1. Children under the age of 12.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e \u003ci\u003eAdults (including the elderly) and children over 12 years of age\u003c\/i\u003e \u003c\/b\u003e VECTAVIR LABIALE should be applied at intervals of approximately 2 hours throughout the day. Treatment, to be continued for 4 days, should be started as soon as possible, at the first sign of infection. However, even in patients who start therapy later, VECTAVIR LABIALE has proven effective in accelerating the healing of lesions, reducing the pain associated with them and shortening the time for viral spread. \u003cb\u003e \u003ci\u003ePediatric population Children (under 12 years of age) \u003c\/i\u003e \u003c\/b\u003e The use of VECTAVIR LABIALE is not recommended in children under 12 years of age due to a lack of data on safety and\/or efficacy.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDo not freeze. Do not store the medicine packaged in the 2 g aluminum tube at temperatures above 25°C. Do not store medicines packaged in the 2 g plastic bottle with dispenser and the 5 g aluminum tube at temperatures above 30°C.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe cream should only be applied to lesions on the lips and around the mouth. It is not recommended for application on mucous membranes (e.g. in the eyes, mouth or nose or on the genitals). Particular care should be taken to avoid application in or near the eyes. Severely immunocompromised patients (e.g. patients with AIDS or bone marrow transplant recipients) should be encouraged to consult a physician if oral therapy is indicated. VECTAVIR LABIALE contains cetostearyl alcohol: it may cause local skin reactions (e.g. contact dermatitis). VECTAVIR LABIALE contains 416 mg of propylene glycol in each gram of cream: it may cause skin irritation.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eExperience in clinical trials has not identified interactions resulting from the concomitant administration of drugs for topical or systemic use and VECTAVIR LABIALE cream.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVECTAVIR LABIALE cream was well tolerated during studies in humans. Experience from clinical trials has shown that there is no difference in the frequency or type of adverse reactions between VECTAVIR LABIALE cream and placebo. The most common events are adverse events in the application area. Adverse reactions are listed below by system organ class, class and frequency. The frequencies are defined as follows: \u003ci\u003eVery common\u003c\/i\u003e (\u0026gt;1\/10); \u003ci\u003ecommon\u003c\/i\u003e (\u003e1\/100 to \u003c1\/10); \u003ci\u003euncommon\u003c\/i\u003e (\u003e1\/1,000 to \u003c1\/100); \u003ci\u003erare\u003c\/i\u003e (\u003e1\/10,000 to \u003c1\/1,000); \u003ci\u003every rare\u003c\/i\u003e (\u0026lt;1\/10.000), \u003ci\u003enot known\u003c\/i\u003e (frequency cannot be estimated from the available data). Within each frequency class, undesirable effects are presented in order of decreasing seriousness.\u003c\/p\u003e\n\u003cp\u003eGeneral pathologies and disorders at the application site.\u003c\/p\u003e\n\u003cp\u003eCommon: Application site reactions (including skin burning sensation, skin pain, hypoesthesia).\u003c\/p\u003e\n\u003cp\u003ePost-marketing surveillance highlighted the following adverse events (all reactions were either localized or general). It is difficult to define a frequency for post-marketing adverse events and therefore events are listed with an unknown frequency\u003c\/p\u003e\n\u003cp\u003eImmune system disorders: Hypersensitivity, urticaria.\u003c\/p\u003e\n\u003cp\u003eSkin and subcutaneous tissue disorders: Allergic dermatitis (including rash, pruritus, blisters and edema).\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eReporting of suspected adverse reactions \u003c\/b\u003e Reporting suspected adverse reactions that occur after authorization of the medicine is important, as it allows continuous monitoring of the benefit\/risk balance of the medicine. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at: http:\/\/www.aifa.gov.it\/content\/segnalazioni-reazioni-avverse\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEven after oral ingestion of the entire contents of a pack of VECTAVIR LABIALE cream, no side effects should occur; penciclovir is poorly absorbed after oral administration. However, irritation of the oral cavity may occur. In case of accidental ingestion, no specific treatment is necessary.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePregnancy\u003c\/b\u003e When the cream is used in pregnant women, there is unlikely to be any cause for concern about adverse effects as the systemic absorption of penciclovir following topical application of VECTAVIR LABIALE cream was found to be minimal (see Section 5.2). As the safety of penciclovir in pregnant women has not been established, VECTAVIR LABIALE cream should be used on the advice of a doctor during pregnancy or by mothers who are breastfeeding, only if the potential benefits outweigh the potential risks associated with treatment. \u003cb\u003eBreastfeeding\u003c\/b\u003e When the cream is used in women who are breastfeeding, there is unlikely to be any cause for concern about adverse effects as systemic absorption of penciclovir following topical application of VECTAVIR LABIALE cream has been found to be minimal (see Section 5.2). There is no information on the excretion of penciclovir in human milk.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eVectavir Labiale does not affect the ability to drive or use machines.\u003c\/p\u003e","brand":"Perrigo","offers":[{"title":"Default Title","offer_id":51730213241159,"sku":"032154015","price":13.48,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/perrigo-italia-srl-vectavir-labiale-1-2-g-crema-farmacia-dottor-tili-1213791003.jpg?v=1767155970"},{"product_id":"aciclovir-mylan-generics-5-3-g-crema","title":"Aciclovir Mylan Generics 5% 3 g cream","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAciclovir Mylan Generics cream is indicated in the treatment of Herpes simplex skin infections such as: primary or recurrent genital herpes and herpes labialis.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eOne gram of cream contains 50 mg of acyclovir. Excipient with known effects: methyl parahydroxybenzoate. For the full list of excipients, see section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTefose 1500, glycerol, stearic acid, liquid paraffin, methyl parahydroxybenzoate, purified water.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eHypersensitivity to the active substance, to valaciclovir or to any of the excipients listed in section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eDosage Aciclovir cream must be applied 5 times a day at intervals of approximately 4 hours. Aciclovir cream should be applied to lesions or areas where infections are developing as soon as possible after the infection has started. It is particularly important to begin treatment of recurrent episodes during the prodrome phase or at the first appearance of lesions. Treatment can also be started during the later stages (papules or vesicles). Treatment must continue for at least 4 days for herpes labialis and for 5 days for genital herpes. If there is no healing, treatment can continue for up to a maximum of 10 days.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eStore at a temperature not exceeding 25°C.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAciclovir cream is not recommended for application to mucous membranes, such as those of the mouth, eyes or vagina, as it may be irritating. Particular care must be taken to avoid accidental introduction into the eyes. Animal studies indicate that application of aciclovir cream into the vagina may cause reversible irritation. In severely immunocompromised patients (e.g. AIDS patients or bone marrow transplant patients), oral administration of acyclovir should be considered. Such patients should be advised to consult their doctor regarding the treatment of any infection. The use of the product, especially if prolonged, can give rise to sensitization phenomena, where this occurs it is necessary to interrupt the treatment and consult the doctor. No phenomena of addiction or dependence on the drug have been reported. Contains methyl parahydroxybenzoate, which may cause allergic reactions (even delayed).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNo clinically significant interactions have been identified.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe following convention was used for the classification of undesirable effects in terms of frequency: very common ≥1\/10, common ≥1\/100 and \u003c1\/10, uncommon 1\/1000 and \u003c1\/100, rare ≥1\/10,000 and \u003c1\/1000, very rare \u003c1\/10,000. Data from clinical trials were used to assign frequency categories to adverse reactions observed during clinical trials with aciclovir 3% ophthalmic ointment. Due to the nature of the adverse events observed, it is not possible to unambiguously determine which events are related to the administration of the drug and which are related to the disease itself. Data from spontaneous reports were used as a basis to determine the frequency of those events observed post-marketing. \u003cb\u003ePathologies of the skin and subcutaneous tissue\u003c\/b\u003e Uncommon: Transient burning or pain after application of aciclovir cream Moderate dryness or peeling of the skin Itching Rare: Erythema. Contact dermatitis following application. Where sensitivity tests were conducted, it was shown that the substances causing reactivity phenomena were the components of the base cream rather than acyclovir. \u003cb\u003eImmune system disorders\u003c\/b\u003e Very rare: Immediate hypersensitivity reactions including angioedema and urticaria \u003cb\u003eReporting of suspected adverse reactions\u003c\/b\u003e Reporting suspected adverse reactions that occur after authorization of the medicine is important, as it allows continuous monitoring of the benefit\/risk balance of the medicine. Healthcare professionals are asked to report any suspected adverse reaction via the national reporting system to the Italian Medicines Agency, Website: http:\/\/www.agenziafarmaco.gov.it\/content\/come-segnalare-una-sospetti-reazione-avversa.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEven if the entire contents of a tube of cream containing 500 mg of aciclovir is ingested, no side effects should occur.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePregnancy The use of aciclovir cream should be considered only when the potential benefits outweigh the possibility of unknown risks. However, systemic exposure following topical application of aciclovir cream is very low. A registry on the use of aciclovir in pregnancy provided data on pregnancy outcomes in women exposed to various post-marketing formulations of aciclovir. These observations did not show an increase in the number of birth anomalies among subjects exposed to aciclovir compared to the general population. All defects found at birth did not show any unique or consistent characteristics that would suggest a common cause. Systemic administration of aciclovir, in internationally accepted conventional tests, did not produce embryotoxic or teratogenic effects in rabbits, rats or mice. In an experimental test not included in standard teratogenicity tests, in rats, fetal abnormalities were observed after subcutaneous doses of acyclovir so high as to produce toxic effects on the mother. The clinical relevance of these findings is uncertain. Breastfeeding Limited data in humans indicate that aciclovir is found in breast milk after systemic administration. However, the dose received by an infant following use of aciclovir cream by the mother should be insignificant. Fertility See clinical studies in paragraphs 5.2 and 5.3.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThere are no known negative effects of aciclovir cream on the ability to drive and use machines.\u003c\/p\u003e","brand":"Mylan","offers":[{"title":"Default Title","offer_id":51730213830983,"sku":"034738017","price":8.65,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/mylan-spa-aciclovir-mylan-generics-5-3-g-crema-farmacia-dottor-tili-1213791353.jpg?v=1767156207"},{"product_id":"aciclovir-eg-5-3-g-crema","title":"Aciclovir EG 5% 3 g cream","description":"\u003cp\u003e\u003cstrong\u003eINDICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eACICLOVIR EG cream is indicated in the treatment of Herpes Simplex skin infections such as: primary or recurrent genital herpes and Herpes labialis.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eACTIVE INGREDIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003e1 g of cream contains\u003c\/u\u003e: \u003ci\u003eActive ingredient:\u003c\/i\u003e acyclovir: 50 mg. Excipients with known effects: 67.5 mg of cetostearyl alcohol, 7.5 mg of sodium lauryl sulfate, 200 mg of propylene glycol (E1520). For the full list of excipients, see section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXCIPIENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePoloxamer 407; Cetostearyl alcohol; Sodium lauryl sulfate; White Vaseline; Liquid paraffin; Sucrose monopalmitate; Propylene glycol (E1520); Purified water.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONTRAINDICATIONS AND SIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eACICLOVIR EG cream is contraindicated in patients with known hypersensitivity to aciclovir, valaciclovir, propylene glycol or any of the excipients listed in section 6.1.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDOSAGE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eACICLOVIR EG CREMA must be applied 5 times a day at intervals of approximately 4 hours. ACICLOVIR EG cream must be applied to the lesions, or to the areas where they are developing, as soon as possible, preferably during the earliest stages (prodromes or erythema). Treatment can also be started during the later stages (papules or vesicles). Treatment must continue for at least 4 days for herpes labialis and for 5 days for genital herpes. If there is no healing, treatment can continue for up to a maximum of 10 days.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eCONSERVATION\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eStore at a temperature not exceeding 25°C.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWARNINGS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAciclovir cream is not recommended for ophthalmic use, nor is application to the mucous membranes of the mouth or vagina as it may be irritating. Particular care should be taken to avoid accidental application into the eyes. Animal studies indicate that the application of ACICLOVIR EG cream into the vagina may cause reversible irritation. In severely immunocompromised patients (patients with AIDS or patients with bone marrow transplant) the administration of acyclovir in oral formulations should be considered. It should be recommended that such patients consult their doctor regarding the treatment of any infection. The use of the product, especially if prolonged, can give rise to sensitization phenomena, if this happens it is necessary to interrupt the treatment and consult the doctor. No phenomena of addiction or dependence on the drug have been reported. \u003ci\u003eImportant information about some excipients\u003c\/i\u003e This medicine contains cetostearyl alcohol which may cause localized skin reactions (e.g. contact dermatitis). This medicine contains 7.5 mg of sodium lauryl sulphate per g of cream. Sodium lauryl sulfate may cause skin irritation (stinging or burning sensation) or intensify skin reactions caused by other medicines when applied to the same area. This medicine contains 200 mg of propylene glycol per g of cream.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNo clinically significant interactions have been identified.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSIDE EFFECTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe following convention was used for the classification of side effects in terms of frequency: very common ≥ 1\/10, common ≥ 1\/100 and \u003c 1\/10, uncommon ≥ 1\/1,000 and \u003c 1\/100, rare ≥ 1\/10,000 and \u003c 1\/1,000, very rare \u003c 1\/10,000. To assign frequency categories to the adverse reactions observed during clinical studies on the use of aciclovir cream, data from these clinical studies were used. Due to the nature of the adverse events observed, it is not possible to unambiguously determine which events are related to the administration of the drug and which are related to the disease itself. Data from spontaneous reports were used as a basis to determine the frequency of those events detected by post-marketing pharmacovigilance. \u003cb\u003ePathologies of the skin and subcutaneous tissue.\u003c\/b\u003e Uncommon: Transient burning or pain after application of aciclovir cream. Moderate dryness and flaking of the skin. Itching. Rare: Erythema. Contact dermatitis after application. Where sensitivity tests had been conducted, it was demonstrated that the substances causing reactivity phenomena were the components of the base cream rather than aciclovir. \u003cb\u003eImmune system disorders.\u003c\/b\u003e Very rare: immediate hypersensitivity reactions including angioedema and urticaria. \u003cb\u003eReporting of suspected adverse reactions\u003c\/b\u003e Reporting suspected adverse reactions that occur after authorization of the medicine is important, as it allows continuous monitoring of the benefit\/risk balance of the medicine. Healthcare professionals are asked to report any suspected adverse reactions via the national reporting system at https:\/\/www.aifa.gov.it\/content\/segnalazioni-reazioni-avverse.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOVERDOSE\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEven if the entire contents of a 10 g tube of cream containing 500 mg of acyclovir are swallowed, no undesirable effects should be expected.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePREGNANCY AND BREASTFEEDING\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFertility See \u003ci\u003eClinical studies\u003c\/i\u003e in paragraph 5.2. Pregnancy The use of aciclovir should only be considered if the potential benefits outweigh the possibility of unknown risks, however, the systemic exposure to aciclovir following topical application of aciclovir cream is very low. A post-marketing registry on the use of aciclovir in pregnancy provided data on pregnancy outcomes in women exposed to various formulations of aciclovir. These observations did not show an increase in the number of birth defects among subjects exposed to aciclovir compared to the general population and all birth defects did not show any particularity or common characteristics, such as to suggest a single cause. Systemic administration of aciclovir in internationally accepted standard tests did not produce embryonic toxicity or teratogenic effects in rabbits, rats or mice. In an experimental test in rats not included in the classic teratogenesis tests, fetal anomalies were observed after subcutaneous doses of acyclovir so high as to produce toxic effects in the mother. However, the clinical relevance of these findings is uncertain. Breastfeeding Limited data indicate that the drug is found in breast milk following systemic administration. However, the dose received by an infant following the use of aciclovir cream by the mother should be insignificant.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEFFECTS ON DRIVING ABILITY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNone known.\u003c\/p\u003e","brand":"Eg","offers":[{"title":"Default Title","offer_id":51730213863751,"sku":"032307047","price":7.44,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0564\/4989\/2467\/files\/eg-spa-aciclovir-eg-5-3-g-crema-farmacia-dottor-tili-1213791352.jpg?v=1767156189"}],"url":"https:\/\/www.dottortili.com\/en-eu\/collections\/farmaci-e-trattamenti-per-herpes-labiale.oembed","provider":"Farmacia Dottor Tili","version":"1.0","type":"link"}